MMP14 Antikörper (C-Term)

Produktnummer ABIN6263294

Produktdetails anti-MMP14 Antikörper

Target: MMP14 (Matrix Metallopeptidase 14 (Membrane-inserted) (MMP14))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MMP14 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)

Spezifität: MMP14 Antibody detects endogenous levels of total MMP14.

Homologie: Pig,Bovine,Horse,Sheep,Rabbit,Dog

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human MMP14, corresponding to a region within C-terminal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:3000, IHC: 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu MMP14

Target: MMP14 (Matrix Metallopeptidase 14 (Membrane-inserted) (MMP14))

Andere Bezeichnung: MMP14 (MMP14 Produkte)

Synonyme: MMP1 antikoerper, MMP-14 antikoerper, MMP-X1 antikoerper, MT-MMP antikoerper, MT-MMP 1 antikoerper, MT1-MMP antikoerper, MT1MMP antikoerper, MTMMP1 antikoerper, mmp-x1 antikoerper, mt1-mmp antikoerper, mtmmp1 antikoerper, AI325305 antikoerper, MT-MMP-1 antikoerper, sabe antikoerper, Mt1-mmp antikoerper, MT-MMPbeta antikoerper, cb386 antikoerper, sb:cb386 antikoerper, wu:fb72b09 antikoerper, mmp14 antikoerper, matrix metallopeptidase 14 antikoerper, matrix metallopeptidase 14 (membrane-inserted) antikoerper, matrix metallopeptidase 14b (membrane-inserted) antikoerper, matrix metallopeptidase 14a (membrane-inserted) antikoerper, matrix metallopeptidase 14 L homeolog antikoerper, MMP14 antikoerper, mmp14 antikoerper, Mmp14 antikoerper, mmp14b antikoerper, mmp14a antikoerper, mmp14.L antikoerper

Hintergrund:

Description: Endopeptidase that degrades various components of the extracellular matrix such as collagen. Activates progelatinase A. Essential for pericellular collagenolysis and modeling of skeletal and extraskeletal connective tissues during development (By similarity). May be involved in actin cytoskeleton reorganization by cleaving PTK7 (PubMed:20837484). Acts as a positive regulator of cell growth and migration via activation of MMP15. Involved in the formation of the fibrovascular tissues in association with pro-MMP2 (PubMed:12714657). Cleaves ADGRB1 to release vasculostatin-40 which inhibits angiogenesis (PubMed:22330140).

Gene: MMP14

Molekulargewicht: 65kDa

Gen-ID: 4323

UniProt: P50281

Pathways: Autophagie