Meningioma 1 Antikörper (Internal Region)
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- Target Alle Meningioma 1 (MN1) Antikörper anzeigen
- Meningioma 1 (MN1) (MN1 proto-oncogene (MN1))
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Bindungsspezifität
- Internal Region
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Reaktivität
- Human, Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser Meningioma 1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)
- Spezifität
- MN1 Antibody detects endogenous levels of total MN1.
- Homologie
- Pig,Horse,Rabbit,Dog,Xenopus
- Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human MN1, corresponding to a region within the internal amino acids.
- Isotyp
- IgG
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- Applikationshinweise
- WB 1:500-1:2000, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20 °C. Stable for 12 months from date of receipt.
- Haltbarkeit
- 12 months
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- Target
- Meningioma 1 (MN1) (MN1 proto-oncogene (MN1))
- Andere Bezeichnung
- MN1 (MN1 Produkte)
- Synonyme
- MGCR antikoerper, MGCR1 antikoerper, MGCR1-PEN antikoerper, dJ353E16.2 antikoerper, MN1 proto-oncogene, transcriptional regulator antikoerper, MN1 antikoerper
- Hintergrund
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Description: Transcriptional activator which specifically regulates expression of TBX22 in the posterior region of the developing palate. Required during later stages of palate development for growth and medial fusion of the palatal shelves. Promotes maturation and normal function of calvarial osteoblasts, including expression of the osteoclastogenic cytokine TNFSF11/RANKL. Necessary for normal development of the membranous bones of the skull (By similarity). May play a role in tumor suppression (Probable).
Gene: MN1
- Molekulargewicht
- 135kDa
- Gen-ID
- 4330
- UniProt
- Q10571
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