MRC2 Antikörper (N-Term)
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- Target Alle MRC2 Antikörper anzeigen
- MRC2 (Mannose Receptor, C Type 2 (MRC2))
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Bindungsspezifität
- N-Term
- Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser MRC2 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
- Spezifität
- MRC2 Antibody detects endogenous levels of total MRC2.
- Homologie
- Pig,Bovine,Horse,Sheep,Rabbit,Dog
- Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human MRC2, corresponding to a region within N-terminal amino acids.
- Isotyp
- IgG
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- Applikationshinweise
- WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20 °C. Stable for 12 months from date of receipt.
- Haltbarkeit
- 12 months
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- Target
- MRC2 (Mannose Receptor, C Type 2 (MRC2))
- Andere Bezeichnung
- MRC2 (MRC2 Produkte)
- Synonyme
- MRC2 antikoerper, cd280 antikoerper, uparap antikoerper, clec13e antikoerper, endo180 antikoerper, Endo180 antikoerper, CD280 antikoerper, CLEC13E antikoerper, ENDO180 antikoerper, UPARAP antikoerper, mKIAA0709 antikoerper, uPARAP antikoerper, mannose receptor C type 2 antikoerper, mannose receptor, C type 2 antikoerper, MRC2 antikoerper, mrc2 antikoerper, Mrc2 antikoerper
- Hintergrund
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Description: May play a role as endocytotic lectin receptor displaying calcium-dependent lectin activity. Internalizes glycosylated ligands from the extracellular space for release in an endosomal compartment via clathrin-mediated endocytosis. May be involved in plasminogen activation system controlling the extracellular level of PLAUR/PLAU, and thus may regulate protease activity at the cell surface. May contribute to cellular uptake, remodeling and degradation of extracellular collagen matrices. May play a role during cancer progression as well as in other chronic tissue destructive diseases acting on collagen turnover. May participate in remodeling of extracellular matrix cooperating with the matrix metalloproteinases (MMPs).
Gene: MRC2
- Molekulargewicht
- 167kDa
- Gen-ID
- 9902
- UniProt
- Q9UBG0
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