CDC42BPB Antikörper (C-Term)
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- Target Alle CDC42BPB Antikörper anzeigen
- CDC42BPB (CDC42 Binding Protein Kinase beta (DMPK-Like) (CDC42BPB))
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Bindungsspezifität
- C-Term
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser CDC42BPB Antikörper ist unkonjugiert
- Applikation
- ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
- Spezifität
- MRCKbeta Antibody detects endogenous levels of total MRCKbeta.
- Homologie
- Pig,Zebrafish,Bovine,Horse,Sheep,Dog
- Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human MRCKbeta, corresponding to a region within C-terminal amino acids.
- Isotyp
- IgG
- Top Product
- Discover our top product CDC42BPB Primärantikörper
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- Applikationshinweise
- WB 1:1000, IHC 1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20 °C. Stable for 12 months from date of receipt.
- Haltbarkeit
- 12 months
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- Target
- CDC42BPB (CDC42 Binding Protein Kinase beta (DMPK-Like) (CDC42BPB))
- Andere Bezeichnung
- CDC42BPB (CDC42BPB Produkte)
- Synonyme
- CDC42BPB antikoerper, wu:fb98c02 antikoerper, wu:fc48b05 antikoerper, wu:fc90d12 antikoerper, si:dkeyp-93h6.2 antikoerper, MRCKb antikoerper, MRCKB antikoerper, CDC42 binding protein kinase beta antikoerper, CDC42 binding protein kinase beta (DMPK-like) antikoerper, CDC42BPB antikoerper, cdc42bpb antikoerper, Cdc42bpb antikoerper
- Hintergrund
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Description: Serine/threonine-protein kinase which is an important downstream effector of CDC42 and plays a role in the regulation of cytoskeleton reorganization and cell migration. Regulates actin cytoskeletal reorganization via phosphorylation of PPP1R12C and MYL9/MLC2 (PubMed:21457715, PubMed:21949762). In concert with MYO18A and LURAP1, is involved in modulating lamellar actomyosin retrograde flow that is crucial to cell protrusion and migration (PubMed:18854160). Phosphorylates PPP1R12A (PubMed:21457715). In concert with FAM89B/LRAP25 mediates the targeting of LIMK1 to the lamellipodium resulting in its activation and subsequent phosphorylation of CFL1 which is important for lamellipodial F-actin regulation (By similarity).
Gene: CDC42BPB
- Molekulargewicht
- 194kDa
- Gen-ID
- 9578
- UniProt
- Q9Y5S2
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