MTM1 Antikörper (C-Term)
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- Target Alle MTM1 Antikörper anzeigen
- MTM1 (Myotubularin 1 (MTM1))
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Bindungsspezifität
- C-Term
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser MTM1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- Spezifität
- MTM1 Antibody detects endogenous levels of total MTM1.
- Homologie
- Pig,Bovine,Horse,Rabbit,Dog,Xenopus
- Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human MTM1, corresponding to a region within C-terminal amino acids.
- Isotyp
- IgG
- Top Product
- Discover our top product MTM1 Primärantikörper
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- Applikationshinweise
- WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20 °C. Stable for 12 months from date of receipt.
- Haltbarkeit
- 12 months
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- Target
- MTM1 (Myotubularin 1 (MTM1))
- Andere Bezeichnung
- MTM1 (MTM1 Produkte)
- Synonyme
- CNM antikoerper, MTMX antikoerper, XLMTM antikoerper, wu:fb19c01 antikoerper, zgc:123266 antikoerper, myotubularin 1 antikoerper, myotubularin 1 S homeolog antikoerper, MTM1 antikoerper, mtm1 antikoerper, mtm1.S antikoerper, Mtm1 antikoerper
- Hintergrund
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Description: Lipid phosphatase which dephosphorylates phosphatidylinositol 3-monophosphate (PI3P) and phosphatidylinositol 3,5-bisphosphate (PI(3,5)P2). Has also been shown to dephosphorylate phosphotyrosine- and phosphoserine-containing peptides. Negatively regulates EGFR degradation through regulation of EGFR trafficking from the late endosome to the lysosome. Plays a role in vacuolar formation and morphology. Regulates desmin intermediate filament assembly and architecture. Plays a role in mitochondrial morphology and positioning. Required for skeletal muscle maintenance but not for myogenesis.
Gene: MTM1
- Molekulargewicht
- 70kDa
- Gen-ID
- 4534
- UniProt
- Q13496
- Pathways
- Inositol Metabolic Process, Skeletal Muscle Fiber Development
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