MYL2 Antikörper (N-Term)
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- Target Alle MYL2 Antikörper anzeigen
- MYL2 (Myosin, Light Chain 2, Regulatory, Cardiac, Slow (MYL2))
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Bindungsspezifität
- N-Term
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser MYL2 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
- Spezifität
- MLC2 Antibody detects endogenous levels of total MLC2.
- Homologie
- Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
- Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human MLC2, corresponding to a region within N-terminal amino acids.
- Isotyp
- IgG
- Top Product
- Discover our top product MYL2 Primärantikörper
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- Applikationshinweise
- WB 1:1000-3000, 1:100-1:500, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20 °C. Stable for 12 months from date of receipt.
- Haltbarkeit
- 12 months
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- Target
- MYL2 (Myosin, Light Chain 2, Regulatory, Cardiac, Slow (MYL2))
- Andere Bezeichnung
- MYL2 (MYL2 Produkte)
- Synonyme
- CMH10 antikoerper, MLC2 antikoerper, 2410014J02Rik antikoerper, MLC-2 antikoerper, Mlc2 antikoerper, MLC-2v antikoerper, Mlc2v antikoerper, Mylpc antikoerper, Mlc-2 antikoerper, myl2 antikoerper, zgc:136848 antikoerper, XMLC2 antikoerper, cmh10 antikoerper, mlc2 antikoerper, G2 antikoerper, MLC-2A antikoerper, MLC2V antikoerper, myosin light chain 2 antikoerper, myosin light chain, phosphorylatable, fast skeletal muscle antikoerper, myosin, light polypeptide 2, regulatory, cardiac, slow antikoerper, myosin, light chain 2b, regulatory, cardiac, slow antikoerper, myosin light chain 2 S homeolog antikoerper, myosin, light chain 2, regulatory, cardiac, slow antikoerper, MYL2 antikoerper, Mylpf antikoerper, Myl2 antikoerper, myl2b antikoerper, myl2.S antikoerper
- Hintergrund
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Description: Contractile protein that plays a role in heart development and function (By similarity). Following phosphorylation, plays a role in cross-bridge cycling kinetics and cardiac muscle contraction by increasing myosin lever arm stiffness and promoting myosin head diffusion, as a consequence of the increase in maximum contraction force and calcium sensitivity of contraction force. These events altogether slow down myosin kinetics and prolong duty cycle resulting in accumulated myosins being cooperatively recruited to actin binding sites to sustain thin filament activation as a means to fine-tune myofilament calcium sensitivity to force (By similarity). During cardiogenesis plays an early role in cardiac contractility by promoting cardiac myofibril assembly (By similarity).
Gene: MYL2
- Molekulargewicht
- 19 kDa
- Gen-ID
- 4633
- UniProt
- P10916
- Pathways
- Myometrial Relaxation and Contraction
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