Myosin XVIIIA Antikörper (Internal Region)
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- Target Alle Myosin XVIIIA (MYO18A) Antikörper anzeigen
- Myosin XVIIIA (MYO18A)
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Bindungsspezifität
- Internal Region
- Reaktivität
- Human, Ratte, Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser Myosin XVIIIA Antikörper ist unkonjugiert
- Applikation
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
- Spezifität
- MYO18A Antibody detects endogenous levels of total MYO18A.
- Homologie
- Bovine,Horse,Sheep,Rabbit,Dog,Chicken
- Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human MYO18A, corresponding to a region within the internal amino acids.
- Isotyp
- IgG
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- Applikationshinweise
- WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20 °C. Stable for 12 months from date of receipt.
- Haltbarkeit
- 12 months
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- Target
- Myosin XVIIIA (MYO18A)
- Andere Bezeichnung
- MYO18A (MYO18A Produkte)
- Synonyme
- myosin-18 antikoerper, MYSPDZ antikoerper, SPR210 antikoerper, MyoPDZ antikoerper, MysPDZ antikoerper, myosin XVIIIa antikoerper, myosin XVIIIA antikoerper, unconventional myosin-XVIIIa antikoerper, myosin XVIIIA L homeolog antikoerper, Myosin XVIIIA antikoerper, myosin xviiia antikoerper, Myo18a antikoerper, MYO18A antikoerper, myo18a antikoerper, LOC100183025 antikoerper, myo18a.L antikoerper, LOC100640961 antikoerper, Bm1_54460 antikoerper, LOAG_04825 antikoerper
- Hintergrund
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Description: May link Golgi membranes to the cytoskeleton and participate in the tensile force required for vesicle budding from the Golgi. Thereby, may play a role in Golgi membrane trafficking and could indirectly give its flattened shape to the Golgi apparatus (PubMed:19837035, PubMed:23345592). Alternatively, in concert with LURAP1 and CDC42BPA/CDC42BPB, has been involved in modulating lamellar actomyosin retrograde flow that is crucial to cell protrusion and migration (PubMed:18854160). May be involved in the maintenance of the stromal cell architectures required for cell to cell contact (By similarity). Regulates trafficking, expression, and activation of innate immune receptors on macrophages. Plays a role to suppress inflammatory responsiveness of macrophages via a mechanism that modulates CD14 trafficking (PubMed:25965346). Acts as a receptor of surfactant-associated protein A (SFTPA1/SP-A) and plays an important role in internalization and clearance of SFTPA1-opsonized S.aureus by alveolar macrophages (PubMed:16087679, PubMed:21123169). Strongly enhances natural killer cell cytotoxicity (PubMed:27467939).
Gene: MYO18A
- Molekulargewicht
- 230 kDa,190 kDa
- Gen-ID
- 399687
- UniProt
- Q92614
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