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Myosin XVIIIA Antikörper (Internal Region)

MYO18A Reaktivität: Human, Ratte, Maus WB, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6263478
  • Target Alle Myosin XVIIIA (MYO18A) Antikörper anzeigen
    Myosin XVIIIA (MYO18A)
    Bindungsspezifität
    • 4
    • 2
    • 1
    • 1
    • 1
    Internal Region
    Reaktivität
    Human, Ratte, Maus
    Wirt
    • 11
    Kaninchen
    Klonalität
    • 11
    Polyklonal
    Konjugat
    • 8
    • 1
    • 1
    • 1
    Dieser Myosin XVIIIA Antikörper ist unkonjugiert
    Applikation
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
    Spezifität
    MYO18A Antibody detects endogenous levels of total MYO18A.
    Homologie
    Bovine,Horse,Sheep,Rabbit,Dog,Chicken
    Aufreinigung
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human MYO18A, corresponding to a region within the internal amino acids.
    Isotyp
    IgG
  • Applikationshinweise
    WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20 °C. Stable for 12 months from date of receipt.
    Haltbarkeit
    12 months
  • Target
    Myosin XVIIIA (MYO18A)
    Andere Bezeichnung
    MYO18A (MYO18A Produkte)
    Synonyme
    myosin-18 antikoerper, MYSPDZ antikoerper, SPR210 antikoerper, MyoPDZ antikoerper, MysPDZ antikoerper, myosin XVIIIa antikoerper, myosin XVIIIA antikoerper, unconventional myosin-XVIIIa antikoerper, myosin XVIIIA L homeolog antikoerper, Myosin XVIIIA antikoerper, myosin xviiia antikoerper, Myo18a antikoerper, MYO18A antikoerper, myo18a antikoerper, LOC100183025 antikoerper, myo18a.L antikoerper, LOC100640961 antikoerper, Bm1_54460 antikoerper, LOAG_04825 antikoerper
    Hintergrund

    Description: May link Golgi membranes to the cytoskeleton and participate in the tensile force required for vesicle budding from the Golgi. Thereby, may play a role in Golgi membrane trafficking and could indirectly give its flattened shape to the Golgi apparatus (PubMed:19837035, PubMed:23345592). Alternatively, in concert with LURAP1 and CDC42BPA/CDC42BPB, has been involved in modulating lamellar actomyosin retrograde flow that is crucial to cell protrusion and migration (PubMed:18854160). May be involved in the maintenance of the stromal cell architectures required for cell to cell contact (By similarity). Regulates trafficking, expression, and activation of innate immune receptors on macrophages. Plays a role to suppress inflammatory responsiveness of macrophages via a mechanism that modulates CD14 trafficking (PubMed:25965346). Acts as a receptor of surfactant-associated protein A (SFTPA1/SP-A) and plays an important role in internalization and clearance of SFTPA1-opsonized S.aureus by alveolar macrophages (PubMed:16087679, PubMed:21123169). Strongly enhances natural killer cell cytotoxicity (PubMed:27467939).

    Gene: MYO18A

    Molekulargewicht
    230 kDa,190 kDa
    Gen-ID
    399687
    UniProt
    Q92614
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