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MYOC Antikörper (Internal Region)

MYOC Reaktivität: Human, Maus, Ratte WB, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6263485
  • Target Alle MYOC Antikörper anzeigen
    MYOC (Myocilin (MYOC))
    Bindungsspezifität
    • 5
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    Internal Region
    Reaktivität
    • 29
    • 14
    • 14
    • 6
    • 2
    Human, Maus, Ratte
    Wirt
    • 25
    • 4
    Kaninchen
    Klonalität
    • 26
    • 3
    Polyklonal
    Konjugat
    • 15
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser MYOC Antikörper ist unkonjugiert
    Applikation
    • 19
    • 13
    • 9
    • 9
    • 7
    • 6
    • 6
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    Spezifität
    MYOC Antibody detects endogenous levels of total MYOC.
    Homologie
    Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Xenopus
    Aufreinigung
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human MYOC, corresponding to a region within the internal amino acids.
    Isotyp
    IgG
    Top Product
    Discover our top product MYOC Primärantikörper
  • Applikationshinweise
    WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20 °C. Stable for 12 months from date of receipt.
    Haltbarkeit
    12 months
  • Target
    MYOC (Myocilin (MYOC))
    Andere Bezeichnung
    MYOC (MYOC Produkte)
    Synonyme
    MYOC antikoerper, MGC136645 antikoerper, zgc:136645 antikoerper, AI957332 antikoerper, GLC1A antikoerper, TIGR antikoerper, GPOA antikoerper, JOAG antikoerper, JOAG1 antikoerper, myocilin antikoerper, Tigr antikoerper, myocilin antikoerper, MYOC antikoerper, myoc antikoerper, Myoc antikoerper
    Hintergrund

    Description: Secreted glycoprotein regulating the activation of different signaling pathways in adjacent cells to control different processes including cell adhesion, cell-matrix adhesion, cytoskeleton organization and cell migration. Promotes substrate adhesion, spreading and formation of focal contacts. Negatively regulates cell-matrix adhesion and stress fiber assembly through Rho protein signal transduction. Modulates the organization of actin cytoskeleton by stimulating the formation of stress fibers through interactions with components of Wnt signaling pathways. Promotes cell migration through activation of PTK2 and the downstream phosphatidylinositol 3-kinase signaling. Plays a role in bone formation and promotes osteoblast differentiation in a dose-dependent manner through mitogen-activated protein kinase signaling. Mediates myelination in the peripheral nervous system through ERBB2/ERBB3 signaling. Plays a role as a regulator of muscle hypertrophy through the components of dystrophin-associated protein complex. Involved in positive regulation of mitochondrial depolarization. Plays a role in neurite outgrowth. May participate in the obstruction of fluid outflow in the trabecular meshwork.

    Gene: MYOC

    Molekulargewicht
    57kDa
    Gen-ID
    4653
    UniProt
    Q99972
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