SCN1A Antikörper (Internal Region)
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- Target Alle SCN1A Antikörper anzeigen
- SCN1A (Sodium Channel, Voltage-Gated, Type I, alpha Subunit (SCN1A))
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Bindungsspezifität
- Internal Region
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Reaktivität
- Human, Ratte, Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser SCN1A Antikörper ist unkonjugiert
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Applikation
- ELISA, Western Blotting (WB)
- Spezifität
- Nav1.1 Antibody detects endogenous levels of total Nav1.1.
- Homologie
- Bovine,Horse,Sheep,Rabbit,Chicken
- Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human Nav1.1, corresponding to a region within the internal amino acids.
- Isotyp
- IgG
- Top Product
- Discover our top product SCN1A Primärantikörper
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- Applikationshinweise
- WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20 °C. Stable for 12 months from date of receipt.
- Haltbarkeit
- 12 months
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- Target
- SCN1A (Sodium Channel, Voltage-Gated, Type I, alpha Subunit (SCN1A))
- Andere Bezeichnung
- SCN1A (SCN1A Produkte)
- Synonyme
- SCN9A antikoerper, SCN1A antikoerper, B230332M13 antikoerper, Nav1.1 antikoerper, EIEE6 antikoerper, FEB3 antikoerper, FEB3A antikoerper, FHM3 antikoerper, GEFSP2 antikoerper, HBSCI antikoerper, NAC1 antikoerper, SCN1 antikoerper, SMEI antikoerper, sodium voltage-gated channel alpha subunit 1 antikoerper, sodium voltage-gated channel alpha subunit 9 antikoerper, sodium channel, voltage-gated, type I, alpha antikoerper, SCN1A antikoerper, SCN9A antikoerper, Scn1a antikoerper
- Hintergrund
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Description: Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na+ ions may pass in accordance with their electrochemical gradient. Plays a key role in brain, probably by regulating the moment when neurotransmitters are released in neurons. Involved in sensory perception of mechanical pain: activation in somatosensory neurons induces pain without neurogenic inflammation and produces hypersensitivity to mechanical, but not thermal stimuli.
Gene: SCN1A
- Molekulargewicht
- 228 kDa
- Gen-ID
- 6323
- UniProt
- P35498
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