NAMPT Antikörper (C-Term)

Produktnummer ABIN6263511

Produktdetails anti-NAMPT Antikörper

Target: NAMPT (Nicotinamide phosphoribosyltransferase (NAMPT))

Bindungsspezifität: C-Term

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NAMPT Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)

Spezifität: NAMPT Antibody detects endogenous levels of total NAMPT.

Homologie: Pig,Bovine,Horse,Sheep,Rabbit,Dog

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human NAMPT, corresponding to a region within C-terminal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu NAMPT

Target: NAMPT (Nicotinamide phosphoribosyltransferase (NAMPT))

Andere Bezeichnung: NAMPT (NAMPT Produkte)

Synonyme: 1110035O14Rik antikoerper, PBEF antikoerper, PBEF1 antikoerper, VF antikoerper, VISFATIN antikoerper, AI314458 antikoerper, AI480535 antikoerper, NAmPRTase antikoerper, Pbef antikoerper, Pbef1 antikoerper, Visfatin antikoerper, visfatin antikoerper, pbef antikoerper, pbef1 antikoerper, nicotinamide phosphoribosyltransferase antikoerper, Nicotinamide phosphoribosyltransferase antikoerper, nicotinamide phosphoribosyltransferase S homeolog antikoerper, NAMPT antikoerper, Nampt antikoerper, nampt antikoerper, Smon_0680 antikoerper, Mrub_2845 antikoerper, Cseg_3704 antikoerper, BC1002_3997 antikoerper, Ftrac_2686 antikoerper, Varpa_5681 antikoerper, Celal_3900 antikoerper, Deima_0880 antikoerper, BC1001_3724 antikoerper, Celly_1696 antikoerper, Clole_1542 antikoerper, Tsp_05934 antikoerper, nampt.S antikoerper

Hintergrund:

Description: Catalyzes the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, an intermediate in the biosynthesis of NAD. It is the rate limiting component in the mammalian NAD biosynthesis pathway. The secreted form behaves both as a cytokine with immunomodulating properties and an adipokine with anti-diabetic properties, it has no enzymatic activity, partly because of lack of activation by ATP, which has a low level in extracellular space and plasma. Plays a role in the modulation of circadian clock function. NAMPT-dependent oscillatory production of NAD regulates oscillation of clock target gene expression by releasing the core clock component: CLOCK-ARNTL/BMAL1 heterodimer from NAD-dependent SIRT1-mediated suppression (By similarity).

Gene: NAMPT

Molekulargewicht: 52kDa

Gen-ID: 10135

UniProt: P43490