NCOR2 Antikörper (C-Term)

Produktnummer ABIN6263545

Produktdetails anti-NCOR2 Antikörper

Target: NCOR2 (Nuclear Receptor Co-Repressor 2 (NCOR2))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NCOR2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Spezifität: NCOR2 Antibody detects endogenous levels of total NCOR2.

Homologie: Pig,Zebrafish,Bovine,Horse,Sheep,Chicken,Xenopus

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human NCOR2, corresponding to a region within C-terminal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu NCOR2

Target: NCOR2 (Nuclear Receptor Co-Repressor 2 (NCOR2))

Andere Bezeichnung: NCOR2 (NCOR2 Produkte)

Synonyme: CTG26 antikoerper, N-CoR2 antikoerper, SMAP270 antikoerper, SMRT antikoerper, SMRTE antikoerper, SMRTE-tau antikoerper, TNRC14 antikoerper, TRAC antikoerper, TRAC-1 antikoerper, TRAC1 antikoerper, N-CoR antikoerper, SMRTe antikoerper, NCOR2 antikoerper, gb:be017685 antikoerper, si:bz71m17.2 antikoerper, smrt antikoerper, ctg26 antikoerper, smrte antikoerper, trac1 antikoerper, tnrc14 antikoerper, trac-1 antikoerper, smrte-tau antikoerper, nuclear receptor corepressor 2 antikoerper, nuclear receptor co-repressor 2 antikoerper, NCOR2 antikoerper, Ncor2 antikoerper, ncor2 antikoerper

Hintergrund:

Description: Transcriptional corepressor. Mediates the transcriptional repression activity of some nuclear receptors by promoting chromatin condensation, thus preventing access of the basal transcription. Isoform 1 and isoform 5 have different affinities for different nuclear receptors. Involved in the regulation BCL6-dependent of the germinal center (GC) reactions, mainly through the control of the GC B-cells proliferation and survival.

Gene: NCOR2

Molekulargewicht: 274 kDa

Gen-ID: 9612

UniProt: Q9Y618

Pathways: Notch Signalweg, Carbohydrate Homeostasis, Chromatin Binding, Regulation of Lipid Metabolism by PPARalpha