Nicastrin Antikörper (C-Term)
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- Target Alle Nicastrin (NCSTN) Antikörper anzeigen
- Nicastrin (NCSTN)
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Bindungsspezifität
- C-Term
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser Nicastrin Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
- Spezifität
- NCSTN Antibody detects endogenous levels of total NCSTN.
- Homologie
- Pig,Bovine,Horse,Sheep,Rabbit,Dog,Xenopus
- Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human NCSTN, corresponding to a region within C-terminal amino acids.
- Isotyp
- IgG
- Top Product
- Discover our top product NCSTN Primärantikörper
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anti-Nicastrin (NCSTN) (AA 16-115) antibody
NCSTN Reaktivität: Human WB, ELISA Wirt: Maus Polyclonal unconjugated
anti-Nicastrin (NCSTN) (AA 429-669) antibodyNCSTN Reaktivität: Human WB, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Nicastrin (NCSTN) (AA 21-120) antibodyNCSTN Reaktivität: Maus WB, ELISA, IF (cc), IF (p), IHC (p), ICC, IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-Nicastrin (NCSTN) (AA 99-133) antibodyNCSTN Reaktivität: Human, Ratte WB Wirt: Kaninchen Polyclonal RB53031 unconjugated
anti-Nicastrin (NCSTN) (AA 1-689) antibodyNCSTN Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
anti-Nicastrin (NCSTN) (AA 16-115) antibodyNCSTN Reaktivität: Human WB, ELISA Wirt: Maus Monoclonal 1E8 unconjugated
anti-Nicastrin (NCSTN) (AA 420-655) antibodyNCSTN Reaktivität: Human WB, IHC, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Nicastrin (NCSTN) (AA 35-534) antibodyNCSTN Reaktivität: Ratte WB, IHC, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Nicastrin (NCSTN) (AA 168-289) antibodyNCSTN Reaktivität: Human, Maus, Ratte, Huhn, Hund WB, IF Wirt: Maus Monoclonal 35-Nicastrin unconjugated
anti-Nicastrin (NCSTN) (N-Term) antibodyNCSTN Reaktivität: Human, Maus, Ratte WB Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
- WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20 °C. Stable for 12 months from date of receipt.
- Haltbarkeit
- 12 months
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- Target
- Nicastrin (NCSTN)
- Andere Bezeichnung
- NCSTN (NCSTN Produkte)
- Hintergrund
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Description: Essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (amyloid-beta precursor protein) (PubMed:10993067, PubMed:12679784, PubMed:25043039, PubMed:26280335). The gamma-secretase complex plays a role in Notch and Wnt signaling cascades and regulation of downstream processes via its role in processing key regulatory proteins, and by regulating cytosolic CTNNB1 levels.
Gene: NCSTN
- Molekulargewicht
- 77kDa
- Gen-ID
- 23385
- UniProt
- Q92542
- Pathways
- Notch Signalweg, Neurotrophin Signalübertragung
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