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Nicastrin Antikörper (C-Term)

NCSTN Reaktivität: Human, Maus, Ratte WB, ELISA, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6263547
  • Target Alle Nicastrin (NCSTN) Antikörper anzeigen
    Nicastrin (NCSTN)
    Bindungsspezifität
    • 15
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reaktivität
    • 36
    • 32
    • 21
    • 5
    • 5
    • 5
    • 1
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 49
    • 3
    Kaninchen
    Klonalität
    • 42
    • 10
    Polyklonal
    Konjugat
    • 20
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Nicastrin Antikörper ist unkonjugiert
    Applikation
    • 38
    • 13
    • 13
    • 8
    • 7
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
    Spezifität
    NCSTN Antibody detects endogenous levels of total NCSTN.
    Homologie
    Pig,Bovine,Horse,Sheep,Rabbit,Dog,Xenopus
    Aufreinigung
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human NCSTN, corresponding to a region within C-terminal amino acids.
    Isotyp
    IgG
    Top Product
    Discover our top product NCSTN Primärantikörper
  • Applikationshinweise
    WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20 °C. Stable for 12 months from date of receipt.
    Haltbarkeit
    12 months
  • Target
    Nicastrin (NCSTN)
    Andere Bezeichnung
    NCSTN (NCSTN Produkte)
    Synonyme
    CG7012 antikoerper, Dmel\\CG7012 antikoerper, Nct antikoerper, Nic antikoerper, S5A antikoerper, ST96B antikoerper, agro antikoerper, dNct antikoerper, nic antikoerper, NCSTN antikoerper, DKFZp469O2418 antikoerper, APH2 antikoerper, 9430068N19Rik antikoerper, AA727311 antikoerper, Aph2 antikoerper, D1Dau13e antikoerper, Kiaa0253 antikoerper, mKIAA0253 antikoerper, nicastrin antikoerper, Nicastrin antikoerper, NCSTN antikoerper, nct antikoerper, ncstn antikoerper, CpipJ_CPIJ001617 antikoerper, Ncstn antikoerper, aph-2 antikoerper
    Hintergrund

    Description: Essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (amyloid-beta precursor protein) (PubMed:10993067, PubMed:12679784, PubMed:25043039, PubMed:26280335). The gamma-secretase complex plays a role in Notch and Wnt signaling cascades and regulation of downstream processes via its role in processing key regulatory proteins, and by regulating cytosolic CTNNB1 levels.

    Gene: NCSTN

    Molekulargewicht
    77kDa
    Gen-ID
    23385
    UniProt
    Q92542
    Pathways
    Notch Signalweg, Neurotrophin Signalübertragung
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