NEIL2 Antikörper (Internal Region)
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- Target Alle NEIL2 Antikörper anzeigen
- NEIL2 (Endonuclease 8-like 2 (NEIL2))
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Bindungsspezifität
- Internal Region
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Reaktivität
- Human, Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser NEIL2 Antikörper ist unkonjugiert
- Applikation
- Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC)
- Spezifität
- NEIL2 Antibody detects endogenous levels of total NEIL2.
- Homologie
- Pig,Bovine,Horse,Sheep,Rabbit,Dog
- Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human NEIL2, corresponding to a region within the internal amino acids.
- Isotyp
- IgG
- Top Product
- Discover our top product NEIL2 Primärantikörper
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- Applikationshinweise
- WB 1:1000-3000, IHC 1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20 °C. Stable for 12 months from date of receipt.
- Haltbarkeit
- 12 months
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- Target
- NEIL2 (Endonuclease 8-like 2 (NEIL2))
- Andere Bezeichnung
- NEIL2 (NEIL2 Produkte)
- Synonyme
- NEH2 antikoerper, NEI2 antikoerper, Gm1212 antikoerper, nei like DNA glycosylase 2 antikoerper, nei like 2 (E. coli) antikoerper, NEIL2 antikoerper, Neil2 antikoerper
- Hintergrund
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Description: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Has DNA glycosylase activity towards 5-hydroxyuracil and other oxidized derivatives of cytosine with a preference for mismatched double-stranded DNA (DNA bubbles). Has low or no DNA glycosylase activity towards thymine glycol, 2-hydroxyadenine, hypoxanthine and 8-oxoguanine. Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
Gene: NEIL2
- Molekulargewicht
- 37 kDa
- Gen-ID
- 252969
- UniProt
- Q969S2
- Pathways
- DNA Reparatur
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