NEURL Antikörper (Internal Region)
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- Target Alle NEURL Antikörper anzeigen
- NEURL (Neuralized Homolog (Drosophila) (NEURL))
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Bindungsspezifität
- Internal Region
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser NEURL Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
- Spezifität
- Neuralized-1 Antibody detects endogenous levels of total Neuralized-1.
- Homologie
- Pig,Bovine,Rabbit
- Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human Neuralized-1, corresponding to a region within the internal amino acids.
- Isotyp
- IgG
- Top Product
- Discover our top product NEURL Primärantikörper
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anti-Neuralized Homolog (Drosophila) (NEURL) (AA 158-186) antibody
NEURL Reaktivität: Human WB, IHC (p) Wirt: Kaninchen Polyclonal RB21920 unconjugated
anti-Neuralized Homolog (Drosophila) (NEURL) (Ser357) antibodyNEURL Reaktivität: Human, Maus, Ratte WB, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Neuralized Homolog (Drosophila) (NEURL) (pTyr1248) antibodyNEURL Reaktivität: Human, Maus, Ratte WB, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Neuralized Homolog (Drosophila) (NEURL) (Internal Region) antibodyNEURL Reaktivität: Human, Maus, Ratte WB, ELISA, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Neuralized Homolog (Drosophila) (NEURL) (Center) antibodyNEURL Reaktivität: Human WB, IHC, IF, IC Wirt: Kaninchen Polyclonal unconjugated
anti-Neuralized Homolog (Drosophila) (NEURL) (Ser351) antibodyNEURL Reaktivität: Human, Maus, Ratte WB, ELISA Wirt: Kaninchen Polyclonal unconjugated
anti-Neuralized Homolog (Drosophila) (NEURL) (pTyr1112) antibodyNEURL Reaktivität: Human, Maus, Ratte WB, ELISA Wirt: Kaninchen Polyclonal unconjugated
anti-Neuralized Homolog (Drosophila) (NEURL) (Ser352) antibodyNEURL Reaktivität: Human, Maus, Ratte WB, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Neuralized Homolog (Drosophila) (NEURL) (pTyr1221), (pTyr1222) antibodyNEURL Reaktivität: Human, Maus, Ratte, Affe WB, ELISA, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Neuralized Homolog (Drosophila) (NEURL) (pTyr1221), (pTyr1222) antibodyNEURL Reaktivität: Human, Maus, Ratte WB, ELISA, IHC, IP Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
- WB 1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20 °C. Stable for 12 months from date of receipt.
- Haltbarkeit
- 12 months
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- Target
- NEURL (Neuralized Homolog (Drosophila) (NEURL))
- Andere Bezeichnung
- NEURL1 (NEURL Produkte)
- Hintergrund
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Description: Plays a role in hippocampal-dependent synaptic plasticity, learning and memory. Involved in the formation of spines and functional synaptic contacts by modulating the translational activity of the cytoplasmic polyadenylation element-binding protein CPEB3. Promotes ubiquitination of CPEB3, and hence induces CPEB3-dependent mRNA translation activation of glutamate receptor GRIA1 and GRIA2. Can function as an E3 ubiquitin-protein ligase to activate monoubiquitination of JAG1 (in vitro), thereby regulating the Notch pathway. Acts as a tumor suppressor, inhibits malignant cell transformation of medulloblastoma (MB) cells by inhibiting the Notch signaling pathway.
Gene: NEURL1
- Molekulargewicht
- 62kDa
- Gen-ID
- 9148
- UniProt
- O76050
- Pathways
- Notch Signalweg, EGFR Signaling Pathway
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