NUMB Antikörper (C-Term)
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- Target Alle NUMB Antikörper anzeigen
- NUMB (Numb Homolog (NUMB))
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Bindungsspezifität
- C-Term
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Reaktivität
- Human, Maus, Ratte, Huhn
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser NUMB Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
- Spezifität
- NUMB Antibody detects endogenous levels of total NUMB.
- Homologie
- Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken
- Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human NUMB, corresponding to a region within C-terminal amino acids.
- Isotyp
- IgG
- Top Product
- Discover our top product NUMB Primärantikörper
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- Applikationshinweise
- WB 1:1000-3000, IF/ICC 1:50-200, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20 °C. Stable for 12 months from date of receipt.
- Haltbarkeit
- 12 months
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- Target
- NUMB (Numb Homolog (NUMB))
- Andere Bezeichnung
- NUMB (NUMB Produkte)
- Synonyme
- C14orf41 antikoerper, S171 antikoerper, c14_5527 antikoerper, Nb antikoerper, NUMB, endocytic adaptor protein antikoerper, numb homolog (Drosophila) antikoerper, NUMB antikoerper, Numb antikoerper, numb antikoerper
- Hintergrund
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Description: Plays a role in the process of neurogenesis. Required throughout embryonic neurogenesis to maintain neural progenitor cells, also called radial glial cells (RGCs), by allowing their daughter cells to choose progenitor over neuronal cell fate. Not required for the proliferation of neural progenitor cells before the onset of neurogenesis. Also involved postnatally in the subventricular zone (SVZ) neurogenesis by regulating SVZ neuroblasts survival and ependymal wall integrity. May also mediate local repair of brain ventricular wall damage.
Gene: NUMB
- Molekulargewicht
- 75 kDa
- Gen-ID
- 8650
- UniProt
- P49757
- Pathways
- Cell-Cell Junction Organization
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