p63 Antikörper (C-Term)
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- Target Alle p63 (TP63) Antikörper anzeigen
- p63 (TP63) (Tumor Protein P63 (TP63))
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Bindungsspezifität
- C-Term
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser p63 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)
- Spezifität
- P63 Antibody detects endogenous levels of total p63.
- Homologie
- Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
- Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human p63, corresponding to a region within C-terminal amino acids.
- Isotyp
- IgG
- Top Product
- Discover our top product TP63 Primärantikörper
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anti-Tumor Protein P63 (TP63) antibody
KO Validated TP63 Reaktivität: Human WB, ICC, IP, IF, IHC (p), IHC (fro), PLA Wirt: Kaninchen Polyclonal unconjugated
anti-Tumor Protein P63 (TP63) (AA 421-680) antibodyTP63 Reaktivität: Human WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Tumor Protein P63 (TP63) (AA 5-17) antibodyTP63 Reaktivität: Human, Maus, Ratte, Rind (Kuh) WB, IHC, StM Wirt: Kaninchen Polyclonal unconjugated
anti-Tumor Protein P63 (TP63) antibodyTP63 Reaktivität: Human IHC, StM Wirt: Maus Monoclonal TP63-2428 unconjugated
anti-Tumor Protein P63 (TP63) (AA 3-106) antibodyTP63 Reaktivität: Human WB, ELISA, Coat Wirt: Maus Monoclonal TP63-1786 unconjugated
anti-Tumor Protein P63 (TP63) (AA 664-680), (C-Term) antibodyTP63 Reaktivität: Human, Ratte WB, ICC, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-Tumor Protein P63 (TP63) antibodyTP63 Reaktivität: Human, Maus IHC, StM Wirt: Maus Monoclonal TP63-11 unconjugated
anti-Tumor Protein P63 (TP63) antibodyTP63 Reaktivität: Human, Maus, Ratte, Affe WB, ELISA, IHC, ICC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Tumor Protein P63 (TP63) (N-Term) antibodyTP63 Reaktivität: Human WB, ELISA Wirt: Kaninchen Polyclonal unconjugated
anti-Tumor Protein P63 (TP63) (pSer455) antibodyTP63 Reaktivität: Human WB, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
- WB: 1:500-1:3000, IF/ICC: 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20 °C. Stable for 12 months from date of receipt.
- Haltbarkeit
- 12 months
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- Target
- p63 (TP63) (Tumor Protein P63 (TP63))
- Andere Bezeichnung
- TP63 (TP63 Produkte)
- Hintergrund
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Description: Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. Isoform 2 activates RIPK4 transcription. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. Involved in Notch signaling by probably inducing JAG1 and JAG2. Plays a role in the regulation of epithelial morphogenesis. The ratio of DeltaN-type and TA*-type isoforms may govern the maintenance of epithelial stem cell compartments and regulate the initiation of epithelial stratification from the undifferentiated embryonal ectoderm. Required for limb formation from the apical ectodermal ridge. Activates transcription of the p21 promoter.
Gene: TP63
- Molekulargewicht
- 77kDa
- Gen-ID
- 8626
- UniProt
- Q9H3D4
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