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PCBP2 Antikörper (Internal Region)

PCBP2 Reaktivität: Human, Maus, Ratte WB, ELISA, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6264064
  • Target Alle PCBP2 Antikörper anzeigen
    PCBP2 (Poly(rC) Binding Protein 2 (PCBP2))
    Bindungsspezifität
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    Reaktivität
    • 35
    • 21
    • 18
    • 6
    • 5
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 32
    • 4
    Kaninchen
    Klonalität
    • 31
    • 5
    Polyklonal
    Konjugat
    • 25
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser PCBP2 Antikörper ist unkonjugiert
    Applikation
    • 24
    • 12
    • 11
    • 10
    • 5
    • 4
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
    Spezifität
    PCBP2 Antibody detects endogenous levels of total PCBP2.
    Homologie
    Pig,Bovine,Horse
    Aufreinigung
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human PCBP2, corresponding to a region within the internal amino acids.
    Isotyp
    IgG
    Top Product
    Discover our top product PCBP2 Primärantikörper
  • Applikationshinweise
    WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20 °C. Stable for 12 months from date of receipt.
    Haltbarkeit
    12 months
  • Target
    PCBP2 (Poly(rC) Binding Protein 2 (PCBP2))
    Andere Bezeichnung
    PCBP2 (PCBP2 Produkte)
    Synonyme
    HNRNPE2 antikoerper, HNRPE2 antikoerper, hnRNP-E2 antikoerper, AW412548 antikoerper, Hnrpx antikoerper, alphaCP-2 antikoerper, PCBP3 antikoerper, fb36h02 antikoerper, wu:fb36h02 antikoerper, zgc:55964 antikoerper, PCBP2 antikoerper, poly(rC) binding protein 2 antikoerper, poly(rC) binding protein 2 L homeolog antikoerper, PCBP2 antikoerper, Pcbp2 antikoerper, pcbp2 antikoerper, pcbp2.L antikoerper
    Hintergrund

    Description: Single-stranded nucleic acid binding protein that binds preferentially to oligo dC. Major cellular poly(rC)-binding protein. Binds also poly(rU). Negatively regulates cellular antiviral responses mediated by MAVS signaling (PubMed:19881509). It acts as an adapter between MAVS and the E3 ubiquitin ligase ITCH, therefore triggering MAVS ubiquitination and degradation (PubMed:19881509).

    Gene: PCBP2

    Molekulargewicht
    39kDa
    Gen-ID
    5094
    UniProt
    Q15366
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