PDE10A Antikörper (N-Term)
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- Target Alle PDE10A Antikörper anzeigen
- PDE10A (phosphodiesterase 10A (PDE10A))
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Bindungsspezifität
- N-Term
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Reaktivität
- Human, Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser PDE10A Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)
- Spezifität
- PDE10A Antibody detects endogenous levels of total PDE10A.
- Homologie
- Pig,Horse,Sheep,Rabbit,Dog,Chicken
- Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human PDE10A, corresponding to a region within N-terminal amino acids.
- Isotyp
- IgG
- Top Product
- Discover our top product PDE10A Primärantikörper
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- Applikationshinweise
- WB 1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20 °C. Stable for 12 months from date of receipt.
- Haltbarkeit
- 12 months
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- Target
- PDE10A (phosphodiesterase 10A (PDE10A))
- Andere Bezeichnung
- PDE10A (PDE10A Produkte)
- Synonyme
- HSPDE10A antikoerper, Pde10a3 antikoerper, phosphodiesterase 10A antikoerper, PDE10A antikoerper, Pde10a antikoerper
- Hintergrund
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Description: Plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides. Can hydrolyze both cAMP and cGMP, but has higher affinity for cAMP and is more efficient with cAMP as substrate. May play a critical role in regulating cAMP and cGMP levels in the striatum, a region of the brain that contributes to the control of movement and cognition.
Gene: PDE10A
- Molekulargewicht
- 75kDa
- Gen-ID
- 10846
- UniProt
- Q9Y233
- Pathways
- cAMP Metabolic Process
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