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PDZK1 Antikörper (C-Term)

PDZK1 Reaktivität: Human, Maus, Ratte WB, ELISA, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6264124
  • Target Alle PDZK1 Antikörper anzeigen
    PDZK1 (PDZ Domain Containing 1 (PDZK1))
    Bindungsspezifität
    • 11
    • 8
    • 7
    • 7
    • 6
    • 3
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reaktivität
    • 63
    • 35
    • 26
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 56
    • 7
    • 1
    • 1
    Kaninchen
    Klonalität
    • 58
    • 7
    Polyklonal
    Konjugat
    • 25
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser PDZK1 Antikörper ist unkonjugiert
    Applikation
    • 49
    • 24
    • 18
    • 13
    • 9
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
    Spezifität
    PDZK1 Antibody detects endogenous levels of total PDZK1.
    Homologie
    Bovine,Sheep,Rabbit,Dog
    Aufreinigung
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human PDZK1, corresponding to a region within C-terminal amino acids.
    Isotyp
    IgG
    Top Product
    Discover our top product PDZK1 Primärantikörper
  • Applikationshinweise
    WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20 °C. Stable for 12 months from date of receipt.
    Haltbarkeit
    12 months
  • Target
    PDZK1 (PDZ Domain Containing 1 (PDZK1))
    Andere Bezeichnung
    PDZK1 (PDZK1 Produkte)
    Synonyme
    xpdzk1 antikoerper, PDZK1 antikoerper, CAP70 antikoerper, CLAMP antikoerper, NHERF-3 antikoerper, NHERF3 antikoerper, PDZD1 antikoerper, 1700023D20Rik antikoerper, 2610507N21Rik antikoerper, 4921513F16Rik antikoerper, AI267131 antikoerper, AI314638 antikoerper, AL022680 antikoerper, D3Ertd537e antikoerper, Pdzd1 antikoerper, mPDZK1 antikoerper, Clamp antikoerper, PDZ domain containing 1 antikoerper, PDZ domain containing 1 L homeolog antikoerper, PDZK1 antikoerper, pdzk1.L antikoerper, pdzk1 antikoerper, Pdzk1 antikoerper
    Hintergrund

    Description: A scaffold protein that connects plasma membrane proteins and regulatory components, regulating their surface expression in epithelial cells apical domains. May be involved in the coordination of a diverse range of regulatory processes for ion transport and second messenger cascades. In complex with SLC9A3R1, may cluster proteins that are functionally dependent in a mutual fashion and modulate the trafficking and the activity of the associated membrane proteins. May play a role in the cellular mechanisms associated with multidrug resistance through its interaction with ABCC2 and PDZK1IP1. May potentiate the CFTR chloride channel activity. Required for normal cell-surface expression of SCARB1. Plays a role in maintaining normal plasma cholesterol levels via its effects on SCARB1. Plays a role in the normal localization and function of the chloride-anion exchanger SLC26A6 to the plasma membrane in the brush border of the proximal tubule of the kidney. May be involved in the regulation of proximal tubular Na+-dependent inorganic phosphate cotransport therefore playing an important role in tubule function (By similarity).

    Gene: PDZK1

    Molekulargewicht
    57kDa
    Gen-ID
    5174
    UniProt
    Q5T2W1
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