POLB Antikörper (C-Term)
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- Target Alle POLB Antikörper anzeigen
- POLB (Polymerase (DNA Directed), beta (POLB))
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Bindungsspezifität
- C-Term
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser POLB Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
- Spezifität
- DNA Polymerase beta Antibody detects endogenous levels of total DNA Polymerase beta.
- Homologie
- Pig,Zebrafish,Bovine,Sheep,Rabbit,Dog,Chicken,Xenopus
- Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human DNA Polymerase beta, corresponding to a region within C-terminal amino acids.
- Isotyp
- IgG
- Top Product
- Discover our top product POLB Primärantikörper
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- Applikationshinweise
- WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20 °C. Stable for 12 months from date of receipt.
- Haltbarkeit
- 12 months
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- Target
- POLB (Polymerase (DNA Directed), beta (POLB))
- Andere Bezeichnung
- POLB (POLB Produkte)
- Synonyme
- wu:fa97a05 antikoerper, zgc:109924 antikoerper, POLB antikoerper, DDBDRAFT_0186152 antikoerper, DDBDRAFT_0215784 antikoerper, DDBDRAFT_0232376 antikoerper, DDB_0186152 antikoerper, DDB_0215784 antikoerper, DDB_0232376 antikoerper, A430088C08Rik antikoerper, polymerase (DNA directed), beta antikoerper, DNA polymerase beta antikoerper, DNA polymerase X family protein antikoerper, polymerase (DNA directed), beta S homeolog antikoerper, polb antikoerper, POLB antikoerper, polB antikoerper, polb.S antikoerper, Polb antikoerper
- Hintergrund
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Description: Repair polymerase that plays a key role in base-excision repair. Has 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity that removes the 5' sugar phosphate and also acts as a DNA polymerase that adds one nucleotide to the 3' end of the arising single-nucleotide gap. Conducts 'gap-filling' DNA synthesis in a stepwise distributive fashion rather than in a processive fashion as for other DNA polymerases.
Gene: POLB
- Molekulargewicht
- 38kDa
- Gen-ID
- 5423
- UniProt
- P06746
- Pathways
- DNA Reparatur
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