POLR2D Antikörper (N-Term)
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- Target Alle POLR2D Antikörper anzeigen
- POLR2D (Polymerase (RNA) II (DNA Directed) Polypeptide D (POLR2D))
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Bindungsspezifität
- N-Term
- Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser POLR2D Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- Spezifität
- POLR2D Antibody detects endogenous levels of total POLR2D.
- Homologie
- Pig,Bovine,Sheep,Rabbit,Dog,Chicken
- Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human POLR2D, corresponding to a region within N-terminal amino acids.
- Isotyp
- IgG
- Top Product
- Discover our top product POLR2D Primärantikörper
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- Applikationshinweise
- WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20 °C. Stable for 12 months from date of receipt.
- Haltbarkeit
- 12 months
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- Target
- POLR2D (Polymerase (RNA) II (DNA Directed) Polypeptide D (POLR2D))
- Andere Bezeichnung
- POLR2D (POLR2D Produkte)
- Synonyme
- wu:fa95b11 antikoerper, zgc:110435 antikoerper, HSRBP4 antikoerper, HSRPB4 antikoerper, RBP4 antikoerper, RPB16 antikoerper, 2310002G05Rik antikoerper, 2610028L19Rik antikoerper, RNA polymerase II subunit D antikoerper, DNA-directed RNA polymerase II 16 kDa polypeptide antikoerper, polymerase (RNA) II (DNA directed) polypeptide D antikoerper, Polr2d antikoerper, CpipJ_CPIJ006734 antikoerper, UREG_01395 antikoerper, LOC100282338 antikoerper, polr2d antikoerper, POLR2D antikoerper
- Hintergrund
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Description: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB4 is part of a subcomplex with RPB7 that binds to a pocket formed by RPB1, RPB2 and RPB6 at the base of the clamp element. The RBP4-RPB7 subcomplex seems to lock the clamp via RPB7 in the closed conformation thus preventing double-stranded DNA to enter the active site cleft. The RPB4-RPB7 subcomplex binds single-stranded DNA and RNA (By similarity).
Gene: POLR2D
- Molekulargewicht
- 16kDa
- Gen-ID
- 5433
- UniProt
- O15514
- Pathways
- Regulatorische RNA Pathways
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