PPP1CB Antikörper
-
- Target Alle PPP1CB Antikörper anzeigen
- PPP1CB (Protein Phosphatase 1, Catalytic Subunit, beta Isoform (PPP1CB))
-
Reaktivität
- Human, Maus, Ratte
-
Wirt
- Kaninchen
-
Klonalität
- Polyklonal
-
Konjugat
- Dieser PPP1CB Antikörper ist unkonjugiert
-
Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- Spezifität
- PPP1CB Antibody detects endogenous levels of total PPP1CB
- Kreuzreaktivität
- Human, Maus, Ratte (Rattus)
- Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human PPP1CB
- Isotyp
- IgG
- Top Product
- Discover our top product PPP1CB Primärantikörper
-
-
- Applikationshinweise
- WB 1:500-1:2000 IHC 1:50-1:200
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20 °C.Stable for 12 months from date of receipt
- Haltbarkeit
- 12 months
-
- Target
- PPP1CB (Protein Phosphatase 1, Catalytic Subunit, beta Isoform (PPP1CB))
- Andere Bezeichnung
- PPP1CB (PPP1CB Produkte)
- Synonyme
- PP-1B antikoerper, PP1B antikoerper, PP1beta antikoerper, PPP1CD antikoerper, 1200010B19 antikoerper, ik:tdsubc_2f2 antikoerper, si:zc214p16.4 antikoerper, wu:fa09h01 antikoerper, wu:fa11e06 antikoerper, xx:tdsubc_2f2 antikoerper, PP2CB antikoerper, Ppp1cb antikoerper, protein phosphatase 1 catalytic subunit beta antikoerper, protein phosphatase 1, catalytic subunit, beta isoform antikoerper, protein phosphatase 1, catalytic subunit, beta isozyme L homeolog antikoerper, protein phosphatase 1, catalytic subunit, beta isozyme antikoerper, serine/threonine-protein phosphatase PP1-beta catalytic subunit antikoerper, protein phosphatase 1B, magnesium dependent, beta isoform antikoerper, PPP1CB antikoerper, Ppp1cb antikoerper, ppp1cb.L antikoerper, ppp1cb antikoerper, LOC100224238 antikoerper, Ppm1b antikoerper
- Hintergrund
-
Description: Protein phosphatase that associates with over 200 regulatory proteins to form highly specific holoenzymes which dephosphorylate hundreds of biological targets. Protein phosphatase (PP1) is essential for cell division, it participates in the regulation of glycogen metabolism, muscle contractility and protein synthesis. Involved in regulation of ionic conductances and long-term synaptic plasticity. Component of the PTW/PP1 phosphatase complex, which plays a role in the control of chromatin structure and cell cycle progression during the transition from mitosis into interphase. In balance with CSNK1D and CSNK1E, determines the circadian period length, through the regulation of the speed and rhythmicity of PER1 and PER2 phosphorylation. May dephosphorylate CSNK1D and CSNK1E. Dephosphorylates the 'Ser-418' residue of FOXP3 in regulatory T-cells (Treg) from patients with rheumatoid arthritis, thereby inactivating FOXP3 and rendering Treg cells functionally defective (PubMed:23396208).
Gene: PPP1CB
- Molekulargewicht
- 37kDa
- Gen-ID
- 5500
- UniProt
- P62140
- Pathways
- M Phase, Cellular Glucan Metabolic Process, Regulation of Carbohydrate Metabolic Process, Lipid Metabolism
-