Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

PRC1 Antikörper (Internal Region)

PRC1 Reaktivität: Human, Maus, Ratte WB, ELISA, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6264405
  • Target Alle PRC1 Antikörper anzeigen
    PRC1 (Protein Regulator of Cytokinesis 1 (PRC1))
    Bindungsspezifität
    • 8
    • 7
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    Reaktivität
    Human, Maus, Ratte
    Wirt
    • 22
    • 4
    Kaninchen
    Klonalität
    • 22
    • 4
    Polyklonal
    Konjugat
    • 12
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser PRC1 Antikörper ist unkonjugiert
    Applikation
    • 11
    • 6
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
    Spezifität
    PRC1 Antibody detects endogenous levels of total PRC1.
    Homologie
    Pig,Horse,Sheep,Xenopus
    Aufreinigung
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human PRC1, corresponding to a region within the internal amino acids.
    Isotyp
    IgG
    Top Product
    Discover our top product PRC1 Primärantikörper
  • Applikationshinweise
    WB 1:1000-3000, IHC 1:200, IF/ICC, ELISA(peptide) 1:20000-1:40000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20 °C. Stable for 12 months from date of receipt.
    Haltbarkeit
    12 months
  • Target
    PRC1 (Protein Regulator of Cytokinesis 1 (PRC1))
    Andere Bezeichnung
    PRC1 (PRC1 Produkte)
    Synonyme
    cb212 antikoerper, prc1 antikoerper, prc1l antikoerper, zgc:55982 antikoerper, zgc:86918 antikoerper, MGC68845 antikoerper, zgc:55664 antikoerper, ase1 antikoerper, ASE1 antikoerper, D7Ertd348e antikoerper, protein regulator of cytokinesis 1 antikoerper, protein regulator of cytokinesis 1a antikoerper, protein regulator of cytokinesis 1 S homeolog antikoerper, protein regulator of cytokinesis 1b antikoerper, PRC1 antikoerper, prc1a antikoerper, prc1.S antikoerper, prc1b antikoerper, CNC07120 antikoerper, prc1 antikoerper, Prc1 antikoerper
    Hintergrund

    Description: Key regulator of cytokinesis that cross-links antiparrallel microtubules at an average distance of 35 nM. Essential for controlling the spatiotemporal formation of the midzone and successful cytokinesis. Required for KIF14 localization to the central spindle and midbody. Required to recruit PLK1 to the spindle. Stimulates PLK1 phosphorylation of RACGAP1 to allow recruitment of ECT2 to the central spindle. Acts as an oncogene for promoting bladder cancer cells proliferation, apoptosis inhibition and carcinogenic progression (PubMed:17409436).

    Gene: PRC1

    Molekulargewicht
    72kDa
    Gen-ID
    9055
    UniProt
    O43663
Sie sind hier:
Kundenservice