PREX1 Antikörper (Internal Region)

Produktnummer ABIN6264416

Produktdetails anti-PREX1 Antikörper

Target: PREX1 (Phosphatidylinositol-3,4,5-Trisphosphate-Dependent Rac Exchange Factor 1 (PREX1))

Bindungsspezifität: Internal Region

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PREX1 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Spezifität: PREX1 Antibody detects endogenous levels of total PREX1.

Homologie: Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human PREX1, corresponding to a region within the internal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:1000-3000, IHC 1:200, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu PREX1

Target: PREX1 (Phosphatidylinositol-3,4,5-Trisphosphate-Dependent Rac Exchange Factor 1 (PREX1))

Andere Bezeichnung: PREX1 (PREX1 Produkte)

Synonyme: MGC68772 antikoerper, P-REX1 antikoerper, G630042G04 antikoerper, Setd6 antikoerper, RGD1306534 antikoerper, phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1 L homeolog antikoerper, phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 1 antikoerper, phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1 antikoerper, prex1.L antikoerper, PREX1 antikoerper, prex1 antikoerper, Prex1 antikoerper

Hintergrund:

Description: Functions as a RAC guanine nucleotide exchange factor (GEF), which activates the Rac proteins by exchanging bound GDP for free GTP. Its activity is synergistically activated by phosphatidylinositol 3,4,5-trisphosphate and the beta gamma subunits of heterotrimeric G protein. May function downstream of heterotrimeric G proteins in neutrophils.

Gene: PREX1

Molekulargewicht: 186 kDa

Gen-ID: 57580

UniProt: Q8TCU6

Pathways: Regulation of Actin Filament Polymerization