Perforin 1 Antikörper (N-Term)
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- Target Alle Perforin 1 (PRF1) Antikörper anzeigen
- Perforin 1 (PRF1) (Perforin 1 (Pore Forming Protein) (PRF1))
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Bindungsspezifität
- N-Term
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser Perforin 1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA
- Spezifität
- PRF1 Antibody detects endogenous levels of total PRF1.
- Homologie
- Horse,Rabbit,Dog
- Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human PRF1, corresponding to a region within N-terminal amino acids.
- Isotyp
- IgG
- Top Product
- Discover our top product PRF1 Primärantikörper
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anti-Perforin 1 (Pore Forming Protein) (PRF1) (AA 280-555) antibody
PRF1 Reaktivität: Human WB, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Perforin 1 (Pore Forming Protein) (PRF1) antibodyPRF1 Reaktivität: Human, Rind (Kuh) FACS, IP, ICC, IHC (fro), IHC (p) Wirt: Maus Monoclonal dG9 unconjugated
anti-Perforin 1 (Pore Forming Protein) (PRF1) antibodyPRF1 Reaktivität: Human, Maus, Ratte WB, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Perforin 1 (Pore Forming Protein) (PRF1) (AA 461-555) antibodyPRF1 Reaktivität: Human WB, ELISA, IP Wirt: Maus Monoclonal 3B4 unconjugated
anti-Perforin 1 (Pore Forming Protein) (PRF1) (AA 40-355) antibodyPRF1 Reaktivität: Maus WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Perforin 1 (Pore Forming Protein) (PRF1) antibody (FITC)PRF1 Reaktivität: Human, Rind (Kuh) FACS Wirt: Maus Monoclonal dG9 FITC
anti-Perforin 1 (Pore Forming Protein) (PRF1) antibody (APC)PRF1 Reaktivität: Human, Rind (Kuh) FACS Wirt: Maus Monoclonal dG9 APC
anti-Perforin 1 (Pore Forming Protein) (PRF1) (AA 98-534) antibodyPRF1 Reaktivität: Maus WB, IP, ICC, IHC (p), IHC (f) Wirt: Ratte Monoclonal CB5-4 unconjugated
anti-Perforin 1 (Pore Forming Protein) (PRF1) (AA 413-552) antibodyPRF1 Reaktivität: Human IHC, ELISA, Coat, StM Wirt: Maus Monoclonal PRF1-2470 unconjugated
anti-Perforin 1 (Pore Forming Protein) (PRF1) (AA 32-316) antibodyPRF1 Reaktivität: Human WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
- WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20 °C. Stable for 12 months from date of receipt.
- Haltbarkeit
- 12 months
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- Target
- Perforin 1 (PRF1) (Perforin 1 (Pore Forming Protein) (PRF1))
- Andere Bezeichnung
- PRF1 (PRF1 Produkte)
- Hintergrund
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Description: Plays a key role in secretory granule-dependent cell death, and in defense against virus-infected or neoplastic cells. Plays an important role in killing other cells that are recognized as non-self by the immune system, e.g. in transplant rejection or some forms of autoimmune disease. Can insert into the membrane of target cells in its calcium-bound form, oligomerize and form large pores. Promotes cytolysis and apoptosis of target cells by facilitating the uptake of cytotoxic granzymes.
Gene: PRF1
- Molekulargewicht
- 61kDa
- Gen-ID
- 5551
- UniProt
- P14222
- Pathways
- Apoptose, Caspase Kaskade in der Apoptose
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