PSMC3 Antikörper

Produktnummer ABIN6264480

Produktdetails anti-PSMC3 Antikörper

Target: PSMC3 (Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 3 (PSMC3))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PSMC3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA, Immunocytochemistry (ICC)

Spezifität: PSMC3 Antibody detects endogenous levels of total PSMC3

Kreuzreaktivität: Human, Maus, Ratte (Rattus)

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human PSMC3

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000 IHC 1:50-1:200, IF/ICC 1:100-1:500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C.Stable for 12 months from date of receipt

Haltbarkeit: 12 months

Details zu PSMC3

Target: PSMC3 (Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 3 (PSMC3))

Andere Bezeichnung: PSMC3 (PSMC3 Produkte)

Synonyme: TBP1 antikoerper, TBP-1 antikoerper, wu:fb39a02 antikoerper, zgc:86713 antikoerper, psmc3 antikoerper, MGC89608 antikoerper, PSMC3 antikoerper, NV15940 antikoerper, 23.m06430 antikoerper, DDBDRAFT_0186002 antikoerper, DDBDRAFT_0232967 antikoerper, DDB_0186002 antikoerper, DDB_0232967 antikoerper, psmc3-b antikoerper, tbp10 antikoerper, psmc3-a antikoerper, proteasome 26S subunit, ATPase 3 antikoerper, proteasome (prosome, macropain) 26S subunit, ATPase 3 antikoerper, 26S protease regulatory subunit 6A antikoerper, 26S protease regulatory subunit 6a antikoerper, 26S protease regulatory subunit 6A-B antikoerper, 26S protease regulatory subunit 6A, putative antikoerper, proteasome 26S subunit, ATPase 3 S homeolog antikoerper, nth-like DNA glycosylase 1 S homeolog antikoerper, PSMC3 antikoerper, Psmc3 antikoerper, HCAG_00069 antikoerper, GL50803_4365 antikoerper, EDI_316920 antikoerper, CpipJ_CPIJ006888 antikoerper, CpipJ_CPIJ006889 antikoerper, CpipJ_CPIJ010864 antikoerper, prs6a antikoerper, psmc3 antikoerper, LOC100115023 antikoerper, BBOV_IV004580 antikoerper, CGB_M2140W antikoerper, psmC3 antikoerper, LOC100637883 antikoerper, psmc3.S antikoerper, nthl1.S antikoerper

Hintergrund:

Description: Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. PSMC3 belongs to the heterohexameric ring of AAA (ATPases associated with diverse cellular activities) proteins that unfolds ubiquitinated target proteins that are concurrently translocated into a proteolytic chamber and degraded into peptides.

Gene: PSMC3

Molekulargewicht: 49kDa

Gen-ID: 5702

UniProt: P17980

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA, Ubiquitin Proteasome Pathway