Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

RAB43 Antikörper (Internal Region)

RAB43 Reaktivität: Human, Maus WB, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6264583
  • Target Alle RAB43 Antikörper anzeigen
    RAB43 (RAB43, Member RAS Oncogene Family (RAB43))
    Bindungsspezifität
    • 3
    • 1
    • 1
    • 1
    • 1
    Internal Region
    Reaktivität
    • 9
    • 1
    • 1
    Human, Maus
    Wirt
    • 6
    • 3
    Kaninchen
    Klonalität
    • 7
    • 2
    Polyklonal
    Konjugat
    • 9
    Dieser RAB43 Antikörper ist unkonjugiert
    Applikation
    • 9
    • 5
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    Spezifität
    RAB43 Antibody detects endogenous levels of total RAB43.
    Homologie
    Pig,Horse
    Aufreinigung
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human RAB43, corresponding to a region within the internal amino acids.
    Isotyp
    IgG
    Top Product
    Discover our top product RAB43 Primärantikörper
  • Applikationshinweise
    WB 1:1000-3000, IHC 1:200, ELISA(peptide) 1:20000-1:40000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20 °C. Stable for 12 months from date of receipt.
    Haltbarkeit
    12 months
  • Target
    RAB43 (RAB43, Member RAS Oncogene Family (RAB43))
    Andere Bezeichnung
    RAB43 (RAB43 Produkte)
    Hintergrund

    Description: The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. The low intrinsic GTPase activity of RAB43 is activated by USP6NL. Involved in retrograde transport from the endocytic pathway to the Golgi apparatus. Involved in the transport of Shiga toxin from early and recycling endosomes to the trans-Golgi network. Required for the structural integrity of the Golgi complex. Plays a role in the maturation of phagosomes that engulf pathogens, such as S.aureus and M.tuberculosis.

    Gene: RAB43

    Molekulargewicht
    23 kDa
    Gen-ID
    339122
    UniProt
    Q86YS6
Sie sind hier:
Kundenservice