RAB8A Antikörper
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- Target Alle RAB8A Antikörper anzeigen
- RAB8A (RAB8A, Member RAS Oncogene Family (RAB8A))
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser RAB8A Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA
- Spezifität
- RAB8A Antibody detects endogenous levels of total RAB8A
- Kreuzreaktivität
- Human, Maus, Ratte (Rattus)
- Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human RAB8A
- Isotyp
- IgG
- Top Product
- Discover our top product RAB8A Primärantikörper
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- Applikationshinweise
- WB 1:1000-3000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20 °C.Stable for 12 months from date of receipt
- Haltbarkeit
- 12 months
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- Target
- RAB8A (RAB8A, Member RAS Oncogene Family (RAB8A))
- Andere Bezeichnung
- RAB8A (RAB8A Produkte)
- Synonyme
- rab8A antikoerper, DDBDRAFT_0206521 antikoerper, DDBDRAFT_0214885 antikoerper, DDB_0206521 antikoerper, DDB_0214885 antikoerper, HSH2D antikoerper, mel antikoerper, rab8 antikoerper, c-mel antikoerper, MEL antikoerper, RAB8 antikoerper, zgc:162699 antikoerper, AA409338 antikoerper, Mel antikoerper, Rab8 antikoerper, rab8A protein antikoerper, Rab GTPase antikoerper, RAB8A, member RAS oncogene family antikoerper, RAB8A, member RAS oncogene family S homeolog antikoerper, rab8A antikoerper, RAB8A antikoerper, rab8a antikoerper, rab8a.S antikoerper, Rab8a antikoerper
- Hintergrund
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Description: The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. That Rab is involved in polarized vesicular trafficking and neurotransmitter release. Together with RAB11A, RAB3IP, the exocyst complex, PARD3, PRKCI, ANXA2, CDC42 and DNMBP promotes transcytosis of PODXL to the apical membrane initiation sites (AMIS), apical surface formation and lumenogenesis (PubMed:20890297). Together with MYO5B and RAB11A participates in epithelial cell polarization (PubMed:21282656). Plays an important role in ciliogenesis (PubMed:21844891). Together with MICALL2, may also regulate adherens junction assembly (By similarity). May play a role in insulin-induced transport to the plasma membrane of the glucose transporter GLUT4 and therefore play a role in glucose homeostasis (By similarity). Involved in autophagy (PubMed:27103069).
Gene: RAB8A
- Molekulargewicht
- 24 kDa
- Gen-ID
- 4218
- UniProt
- P61006
- Pathways
- M Phase, Regulation of long-term Neuronal Synaptic Plasticity, SARS-CoV-2 Protein Interaktom
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