RAD21 Antikörper (C-Term)
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- Target Alle RAD21 Antikörper anzeigen
- RAD21 (RAD21 Homolog (RAD21))
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Bindungsspezifität
- C-Term
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Reaktivität
- Human, Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser RAD21 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
- Spezifität
- Rad21 Antibody detects endogenous levels of total Rad21.
- Homologie
- Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
- Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human Rad21, corresponding to a region within C-terminal amino acids.
- Isotyp
- IgG
- Top Product
- Discover our top product RAD21 Primärantikörper
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anti-RAD21 Homolog (RAD21) (Center) antibody
RAD21 Reaktivität: Human, Maus WB, IF, IP, IHC (p), ICC Wirt: Kaninchen Polyclonal unconjugated
anti-RAD21 Homolog (RAD21) (AA 287-403) antibodyRAD21 Reaktivität: Human WB, ELISA, IHC, FACS, ICC Wirt: Maus Monoclonal 1B6D1 unconjugated
anti-RAD21 Homolog (RAD21) antibodyRAD21 Reaktivität: Human WB, IHC, IF, IP, ChIP Wirt: Kaninchen Polyclonal unconjugated
anti-RAD21 Homolog (RAD21) antibodyRAD21 Reaktivität: Human WB, ChIP Wirt: Kaninchen Monoclonal unconjugated
anti-RAD21 Homolog (RAD21) (AA 373-422) antibodyRAD21 Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Pferd, Kaninchen, Meerschweinchen, Affe, Huhn, Fledermaus, Schwein, Xenopus laevis WB Wirt: Kaninchen Polyclonal unconjugated
anti-RAD21 Homolog (RAD21) (C-Term) antibodyRAD21 Reaktivität: Human, Maus, Ratte, Rind (Kuh), Zebrafisch (Danio rerio) WB, IHC, IF, IC Wirt: Kaninchen Polyclonal unconjugated
anti-RAD21 Homolog (RAD21) (C-Term) antibodyRAD21 Reaktivität: Human, Maus, Hamster WB, IF Wirt: Kaninchen Polyclonal unconjugated
anti-RAD21 Homolog (RAD21) (AA 531-631) antibodyRAD21 Reaktivität: Human, Ratte WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-RAD21 Homolog (RAD21) (AA 501-535) antibodyRAD21 Reaktivität: Human, Maus, Ratte WB Wirt: Kaninchen Polyclonal RB56184 unconjugated
anti-RAD21 Homolog (RAD21) (AA 178-227) antibodyRAD21 Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Pferd, Kaninchen, Meerschweinchen, Affe, Huhn, Fledermaus, Schwein WB Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
- WB 1:1000-3000, IHC 1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20 °C. Stable for 12 months from date of receipt.
- Haltbarkeit
- 12 months
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- Target
- RAD21 (RAD21 Homolog (RAD21))
- Andere Bezeichnung
- RAD21 (RAD21 Produkte)
- Hintergrund
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Description: Cleavable component of the cohesin complex, involved in chromosome cohesion during cell cycle, in DNA repair, and in apoptosis. The cohesin complex is required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At metaphase-anaphase transition, this protein is cleaved by separase/ESPL1 and dissociates from chromatin, allowing sister chromatids to segregate. The cohesin complex may also play a role in spindle pole assembly during mitosis. Also plays a role in apoptosis, via its cleavage by caspase-3/CASP3 or caspase-7/CASP7 during early steps of apoptosis: the C-terminal 64 kDa cleavage product may act as a nuclear signal to initiate cytoplasmic events involved in the apoptotic pathway.
Gene: RAD21
- Molekulargewicht
- 130kDa
- Gen-ID
- 5885
- UniProt
- O60216
- Pathways
- Positive Regulation of Endopeptidase Activity
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