RCC1 Antikörper (N-Term)
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- Target Alle RCC1 Antikörper anzeigen
- RCC1 (Regulator of Chromosome Condensation 1 (RCC1))
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Bindungsspezifität
- N-Term
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser RCC1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA
- Spezifität
- RCC1 Antibody detects endogenous levels of total RCC1.
- Homologie
- Pig,Bovine,Horse,Sheep,Rabbit,Dog
- Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human RCC1, corresponding to a region within N-terminal amino acids.
- Isotyp
- IgG
- Top Product
- Discover our top product RCC1 Primärantikörper
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- Applikationshinweise
- WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20 °C. Stable for 12 months from date of receipt.
- Haltbarkeit
- 12 months
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- Target
- RCC1 (Regulator of Chromosome Condensation 1 (RCC1))
- Andere Bezeichnung
- RCC1 (RCC1 Produkte)
- Synonyme
- Chc1 antikoerper, zgc:65796 antikoerper, zgc:77114 antikoerper, wu:fj77f08 antikoerper, rcc1 antikoerper, chc1-a antikoerper, BJ1 antikoerper, CG10480 antikoerper, CG18640 (Bj1) antikoerper, Dmel\\CG10480 antikoerper, RCC1 antikoerper, RanGEF antikoerper, Rcc1 antikoerper, dRCC1 antikoerper, inxs antikoerper, sdt antikoerper, xrcc1 antikoerper, chc1-b antikoerper, MGC115703 antikoerper, MGC132085 antikoerper, CHC1 antikoerper, RCC1-I antikoerper, SNHG3-RCC1 antikoerper, 4931417M11Rik antikoerper, AI326872 antikoerper, regulator of chromosome condensation 1 antikoerper, regulator of chromosome condensation 1 L homeolog antikoerper, Regulator of chromosome condensation 1 antikoerper, N terminal fragment of RCC1; similar to S. cerevisiae SRM1 (YGL097W) guanine nucleotide exchange factor for Gsp1 GTPase involved in assembly of nuclear pore complex; frameshifted antikoerper, regulator of chromosome condensation 1 S homeolog antikoerper, rcc1 antikoerper, RCC1 antikoerper, rcc1.L antikoerper, Rcc1 antikoerper, rcc1.S antikoerper
- Hintergrund
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Description: Guanine-nucleotide releasing factor that promotes the exchange of Ran-bound GDP by GTP, and thereby plays an important role in RAN-mediated functions in nuclear import and mitosis (PubMed:1944575, PubMed:17435751, PubMed:20668449, PubMed:22215983, PubMed:11336674). Contributes to the generation of high levels of chromosome-associated, GTP-bound RAN, which is important for mitotic spindle assembly and normal progress through mitosis (PubMed:12194828, PubMed:17435751, PubMed:22215983). Via its role in maintaining high levels of GTP-bound RAN in the nucleus, contributes to the release of cargo proteins from importins after nuclear import (PubMed:22215983). Involved in the regulation of onset of chromosome condensation in the S phase (PubMed:3678831). Binds both to the nucleosomes and double-stranded DNA (PubMed:17435751, PubMed:18762580).
Gene: RCC1
- Molekulargewicht
- ?45 kDa
- Gen-ID
- 1104
- UniProt
- P18754
- Pathways
- Chromatin Binding, Protein targeting to Nucleus
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