RGS17 Antikörper (N-Term)
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- Target Alle RGS17 Antikörper anzeigen
- RGS17 (Regulator of G-Protein Signaling 17 (RGS17))
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Bindungsspezifität
- N-Term
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Reaktivität
- Human, Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser RGS17 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- Spezifität
- RGS17 Antibody detects endogenous levels of total RGS17.
- Homologie
- Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
- Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human RGS17, corresponding to a region within N-terminal amino acids.
- Isotyp
- IgG
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- Applikationshinweise
- WB 1:1000-3000, IHC 1:200, ELISA(peptide) 1:20000-1:40000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20 °C. Stable for 12 months from date of receipt.
- Haltbarkeit
- 12 months
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- Target
- RGS17 (Regulator of G-Protein Signaling 17 (RGS17))
- Andere Bezeichnung
- RGS17 (RGS17 Produkte)
- Synonyme
- RGS17 antikoerper, zgc:92802 antikoerper, MGC179306 antikoerper, RGS-17 antikoerper, RGSZ2 antikoerper, hRGS17 antikoerper, 6430507P11Rik antikoerper, Rgsz2 antikoerper, regulator of G protein signaling 17 antikoerper, regulator of G-protein signaling 17 antikoerper, RGS17 antikoerper, Rgs17 antikoerper, rgs17 antikoerper
- Hintergrund
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Description: Regulates G protein-coupled receptor signaling cascades, including signaling via muscarinic acetylcholine receptor CHRM2 and dopamine receptor DRD2. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form (PubMed:15096504). Binds selectively to GNAZ and GNAI2 subunits, accelerates their GTPase activity and regulates their signaling activities. Negatively regulates mu-opioid receptor-mediated activation of the G-proteins (By similarity).
Gene: RGS17
- Molekulargewicht
- 24 kDa
- Gen-ID
- 26575
- UniProt
- Q9UGC6
- Pathways
- Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling
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