ARHGAP24 Antikörper (Internal Region)
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- Target Alle ARHGAP24 Antikörper anzeigen
- ARHGAP24 (rho GTPase Activating Protein 24 (ARHGAP24))
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Bindungsspezifität
- Internal Region
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser ARHGAP24 Antikörper ist unkonjugiert
- Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- Spezifität
- RHG24 Antibody detects endogenous levels of total RHG24.
- Homologie
- Bovine,Horse,Sheep,Rabbit,Dog
- Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human RHG24, corresponding to a region within the internal amino acids.
- Isotyp
- IgG
- Top Product
- Discover our top product ARHGAP24 Primärantikörper
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- Applikationshinweise
- WB 1:1000-3000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20 °C. Stable for 12 months from date of receipt.
- Haltbarkeit
- 12 months
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- Target
- ARHGAP24 (rho GTPase Activating Protein 24 (ARHGAP24))
- Andere Bezeichnung
- ARHGAP24 (ARHGAP24 Produkte)
- Synonyme
- FILGAP antikoerper, RC-GAP72 antikoerper, RCGAP72 antikoerper, p73 antikoerper, p73RhoGAP antikoerper, 0610025G21Rik antikoerper, si:ch211-65i12.2 antikoerper, Rho GTPase activating protein 24 antikoerper, ARHGAP24 antikoerper, Arhgap24 antikoerper, arhgap24 antikoerper
- Hintergrund
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Description: Rho GTPase-activating protein involved in cell polarity, cell morphology and cytoskeletal organization. Acts as a GTPase activator for the Rac-type GTPase by converting it to an inactive GDP-bound state. Controls actin remodeling by inactivating Rac downstream of Rho leading to suppress leading edge protrusion and promotes cell retraction to achieve cellular polarity. Able to suppress RAC1 and CDC42 activity in vitro. Overexpression induces cell rounding with partial or complete disruption of actin stress fibers and formation of membrane ruffles, lamellipodia, and filopodia. Isoform 2 is a vascular cell-specific GAP involved in modulation of angiogenesis.
Gene: ARHGAP24
- Molekulargewicht
- 84 kDa
- Gen-ID
- 83478
- UniProt
- Q8N264
- Pathways
- Regulation of Cell Size, Positive Regulation of Response to DNA Damage Stimulus
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