RNF19A Antikörper (N-Term)
Kurzübersicht für RNF19A Antikörper (N-Term) (ABIN6264786)
Target
Alle RNF19A Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- N-Term
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Spezifität
- RNF19A Antibody detects endogenous levels of total RNF19A.
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Homologie
- Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken
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Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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Immunogen
- A synthesized peptide derived from human RNF19A, corresponding to a region within N-terminal amino acids.
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Isotyp
- IgG
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Applikationshinweise
- WB 1:1000-3000, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20 °C. Stable for 12 months from date of receipt.
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Haltbarkeit
- 12 months
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- RNF19A (Ring Finger Protein 19A (RNF19A))
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Andere Bezeichnung
- RNF19A
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Hintergrund
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Description: E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes UBE2L3 and UBE2L6 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates, such as SNCAIP or CASR. Specifically ubiquitinates pathogenic SOD1 variants, which leads to their proteasomal degradation and to neuronal protection.
Gene: RNF19A
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Molekulargewicht
- 90 kDa
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Gen-ID
- 25897
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UniProt
- Q9NV58
Target
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