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RRM2 Antikörper (C-Term)

RRM2 Reaktivität: Human, Maus, Ratte WB, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6264868
  • Target Alle RRM2 Antikörper anzeigen
    RRM2 (Ribonucleotide Reductase M2 (RRM2))
    Bindungsspezifität
    • 15
    • 8
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reaktivität
    • 54
    • 13
    • 12
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 49
    • 5
    Kaninchen
    Klonalität
    • 42
    • 12
    Polyklonal
    Konjugat
    • 22
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser RRM2 Antikörper ist unkonjugiert
    Applikation
    • 37
    • 13
    • 13
    • 13
    • 9
    • 8
    • 5
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    Spezifität
    RRM2 Antibody detects endogenous levels of total RRM2.
    Homologie
    Bovine,Horse,Chicken
    Aufreinigung
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human RRM2, corresponding to a region within C-terminal amino acids.
    Isotyp
    IgG
    Top Product
    Discover our top product RRM2 Primärantikörper
  • Applikationshinweise
    WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20 °C. Stable for 12 months from date of receipt.
    Haltbarkeit
    12 months
  • Xia, Wang, Song, Meng, Huang, Huang: "Gambogic acid sensitizes gemcitabine efficacy in pancreatic cancer by reducing the expression of ribonucleotide reductase subunit-M2 (RRM2)." in: Journal of experimental & clinical cancer research : CR, Vol. 36, Issue 1, pp. 107, (2018) (PubMed).

  • Target
    RRM2 (Ribonucleotide Reductase M2 (RRM2))
    Andere Bezeichnung
    RRM2 (RRM2 Produkte)
    Synonyme
    R2 antikoerper, RR2 antikoerper, RR2M antikoerper, AA407299 antikoerper, rrm2 antikoerper, rr2m antikoerper, cb111 antikoerper, chunp6884 antikoerper, r2 antikoerper, ribonucleotide reductase regulatory subunit M2 antikoerper, ribonucleotide reductase M2 antikoerper, ribonucleotide reductase M2, gene 2 L homeolog antikoerper, ribonucleotide reductase M2, gene 1 antikoerper, ribonucleotide reductase M2 polypeptide antikoerper, RRM2 antikoerper, Rrm2 antikoerper, rrm2.2.L antikoerper, rrm2.1 antikoerper, rrm2 antikoerper
    Hintergrund

    Description: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. Inhibits Wnt signaling.

    Gene: RRM2

    Molekulargewicht
    45kDa
    Gen-ID
    6241
    UniProt
    P31350
    Pathways
    Mitotic G1-G1/S Phases
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