RUNX2 Antikörper (Internal Region)
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- Target Alle RUNX2 Antikörper anzeigen
- RUNX2 (Runt-Related Transcription Factor 2 (RUNX2))
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Bindungsspezifität
- Internal Region
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser RUNX2 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
- Spezifität
- RUNX2 Antibody detects endogenous levels of total RUNX2.
- Homologie
- Pig,Bovine,Horse,Sheep,Rabbit,Chicken,Xenopus
- Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human RUNX2, corresponding to a region within the internal amino acids.
- Isotyp
- IgG
- Top Product
- Discover our top product RUNX2 Primärantikörper
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anti-Runt-Related Transcription Factor 2 (RUNX2) (AA 251-350) antibody
RUNX2 Reaktivität: Human WB, ELISA, IF, IHC (p) Wirt: Maus Monoclonal 1D8 unconjugated
anti-Runt-Related Transcription Factor 2 (RUNX2) (AA 251-350) antibodyRUNX2 Reaktivität: Human WB, ELISA, IF, IHC (p) Wirt: Maus Monoclonal 3F5 unconjugated
anti-Runt-Related Transcription Factor 2 (RUNX2) (AA 242-521) antibodyRUNX2 Reaktivität: Human WB, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Runt-Related Transcription Factor 2 (RUNX2) (N-Term) antibodyRUNX2 Reaktivität: Human, Maus, Ratte, Rind (Kuh), Meerschweinchen, Pferd, Zebrafisch (Danio rerio) WB Wirt: Kaninchen Polyclonal unconjugated
anti-Runt-Related Transcription Factor 2 (RUNX2) (AA 445-474) antibodyRUNX2 Reaktivität: Human WB, ELISA, IHC, FACS Wirt: Kaninchen Polyclonal unconjugated
anti-Runt-Related Transcription Factor 2 (RUNX2) (AA 251-351) antibodyRUNX2 Reaktivität: Human, Ratte WB, IF, IHC (p), EIA Wirt: Maus Monoclonal 3F5 unconjugated
anti-Runt-Related Transcription Factor 2 (RUNX2) (AA 445-474) antibodyRUNX2 Reaktivität: Human WB, FACS, IHC (p) Wirt: Kaninchen Polyclonal RB15321 unconjugated
anti-Runt-Related Transcription Factor 2 (RUNX2) (AA 251-351) antibodyRUNX2 Reaktivität: Human WB, ELISA, IHC, IF, IHC (p) Wirt: Maus Monoclonal 1D8 unconjugated
anti-Runt-Related Transcription Factor 2 (RUNX2) antibodyRUNX2 Reaktivität: Human WB, IP Wirt: Kaninchen Monoclonal unconjugated
anti-Runt-Related Transcription Factor 2 (RUNX2) (AA 251-351) antibodyRUNX2 Reaktivität: Human WB, IF, IHC (p), EIA Wirt: Maus Monoclonal 1D2 unconjugated
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- Applikationshinweise
- WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20 °C. Stable for 12 months from date of receipt.
- Haltbarkeit
- 12 months
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- Target
- RUNX2 (Runt-Related Transcription Factor 2 (RUNX2))
- Andere Bezeichnung
- RUNX2 (RUNX2 Produkte)
- Hintergrund
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Description: Transcription factor involved in osteoblastic differentiation and skeletal morphogenesis (PubMed:28505335, PubMed:28738062, PubMed:28703881). Essential for the maturation of osteoblasts and both intramembranous and endochondral ossification. CBF binds to the core site, 5'-PYGPYGGT-3', of a number of enhancers and promoters, including murine leukemia virus, polyomavirus enhancer, T-cell receptor enhancers, osteocalcin, osteopontin, bone sialoprotein, alpha 1(I) collagen, LCK, IL-3 and GM-CSF promoters. In osteoblasts, supports transcription activation: synergizes with SPEN/MINT to enhance FGFR2-mediated activation of the osteocalcin FGF-responsive element (OCFRE) (By similarity). Inhibits KAT6B-dependent transcriptional activation.
Gene: RUNX2
- Molekulargewicht
- 56 kDa
- Gen-ID
- 860
- UniProt
- Q13950
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