SENP2 Antikörper

Produktnummer ABIN6264984

Produktdetails anti-SENP2 Antikörper

Target: SENP2 (SUMO1/sentrin/SMT3 Specific Peptidase 2 (SENP2))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SENP2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Spezifität: SENP2 Antibody detects endogenous levels of total SENP2

Kreuzreaktivität: Human, Maus, Ratte (Rattus)

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human SENP2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:1000-3000 IF/ICC 1:200-1:500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C.Stable for 12 months from date of receipt

Haltbarkeit: 12 months

Details zu SENP2

Target: SENP2 (SUMO1/sentrin/SMT3 Specific Peptidase 2 (SENP2))

Andere Bezeichnung: SENP2 (SENP2 Produkte)

Synonyme: 2310007L05Rik antikoerper, 4930538C18Rik antikoerper, AI646780 antikoerper, AW554757 antikoerper, Smt3ip2 antikoerper, SuPr-1 antikoerper, mKIAA1331 antikoerper, AXAM2 antikoerper, SMT3IP2 antikoerper, Axam antikoerper, SUMO/sentrin specific peptidase 2 antikoerper, SUMO1/sentrin/SMT3 specific peptidase 2 antikoerper, Sumo1/sentrin/SMT3 specific peptidase 2 antikoerper, Senp2 antikoerper, SENP2 antikoerper

Hintergrund:

Description: Protease that catalyzes two essential functions in the SUMO pathway. The first is the hydrolysis of an alpha-linked peptide bond at the C-terminal end of the small ubiquitin-like modifier (SUMO) propeptides, SUMO1, SUMO2 and SUMO3 leading to the mature form of the proteins. The second is the deconjugation of SUMO1, SUMO2 and SUMO3 from targeted proteins, by cleaving an epsilon-linked peptide bond between the C-terminal glycine of the mature SUMO and the lysine epsilon-amino group of the target protein. May down-regulate CTNNB1 levels and thereby modulate the Wnt pathway. Deconjugates SUMO2 from MTA1. Plays a dynamic role in adipogenesis by desumoylating and promoting the stabilization of CEBPB (PubMed:20194620).

Gene: SENP2

Molekulargewicht: 68 kDa

Gen-ID: 59343

UniProt: Q9HC62

Pathways: Chromatin Binding