SH3PXD2A Antikörper (N-Term)

Produktnummer ABIN6265058

Produktdetails anti-SH3PXD2A Antikörper

Target: SH3PXD2A (SH3 and PX Domains 2A (SH3PXD2A))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SH3PXD2A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Spezifität: SH3PXD2A Antibody detects endogenous levels of total SH3PXD2A.

Homologie: Pig,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human SH3PXD2A, corresponding to a region within N-terminal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu SH3PXD2A

Target: SH3PXD2A (SH3 and PX Domains 2A (SH3PXD2A))

Andere Bezeichnung: SH3PXD2A (SH3PXD2A Produkte)

Synonyme: FISH antikoerper, SH3MD1 antikoerper, TKS5 antikoerper, 2310014D11Rik antikoerper, AA589508 antikoerper, AI256723 antikoerper, AI413738 antikoerper, C230050L11 antikoerper, EG329070 antikoerper, Fish antikoerper, Gm5098 antikoerper, Sh3md1 antikoerper, TSK5 antikoerper, Tks5 antikoerper, sh3pxd2a antikoerper, si:dkey-82d4.2 antikoerper, SH3 and PX domains 2A antikoerper, SH3 and PX domains 2Aa antikoerper, SH3PXD2A antikoerper, Sh3pxd2a antikoerper, sh3pxd2aa antikoerper

Hintergrund:

Description: Adapter protein involved in invadopodia and podosome formation, extracellular matrix degradation and invasiveness of some cancer cells. Binds matrix metalloproteinases (ADAMs), NADPH oxidases (NOXs) and phosphoinositides. Acts as an organizer protein that allows NOX1- or NOX3-dependent reactive oxygen species (ROS) generation and ROS localization. In association with ADAM12, mediates the neurotoxic effect of amyloid-beta peptide.

Gene: SH3PXD2A

Molekulargewicht: 125 kDa

Gen-ID: 9644

UniProt: Q5TCZ1