SHP1 Antikörper (C-Term)
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- Target Alle SHP1 (PTPN6) Antikörper anzeigen
- SHP1 (PTPN6) (Protein-tyrosine Phosphatase 1C (PTPN6))
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Bindungsspezifität
- C-Term
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser SHP1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
- Spezifität
- SHP1 Antibody detects endogenous levels of total SHP1.
- Homologie
- Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken
- Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human SHP1, corresponding to a region within C-terminal amino acids.
- Isotyp
- IgG
- Top Product
- Discover our top product PTPN6 Primärantikörper
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anti-Protein-tyrosine Phosphatase 1C (PTPN6) antibody
PTPN6 Reaktivität: Human WB, IHC (p), IP, IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-Protein-tyrosine Phosphatase 1C (PTPN6) antibodyPTPN6 Reaktivität: Human WB, IHC, IF, FACS, StM Wirt: Maus Monoclonal CPTC-APEX1-2 unconjugated
anti-Protein-tyrosine Phosphatase 1C (PTPN6) (AA 247-277) antibodyPTPN6 Reaktivität: Human WB, IF, IHC (p) Wirt: Kaninchen Polyclonal RB17225 unconjugated
anti-Protein-tyrosine Phosphatase 1C (PTPN6) (AA 1-595) antibodyPTPN6 Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
anti-Protein-tyrosine Phosphatase 1C (PTPN6) (AA 243-541) antibodyPTPN6 Reaktivität: Human ELISA, FACS, ICC Wirt: Maus Monoclonal 2E9E4 unconjugated
anti-Protein-tyrosine Phosphatase 1C (PTPN6) (AA 1-597), (Isoform 2) antibodyPTPN6 Reaktivität: Human WB, ELISA, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Protein-tyrosine Phosphatase 1C (PTPN6) (pTyr536) antibodyPTPN6 Reaktivität: Human, Maus, Ratte WB, ELISA, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Protein-tyrosine Phosphatase 1C (PTPN6) (AA 100-400) antibodyPTPN6 Reaktivität: Human WB, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Protein-tyrosine Phosphatase 1C (PTPN6) (AA 492-597) antibodyPTPN6 Reaktivität: Human, Maus, Ratte, Hund WB, IHC, IF, IP Wirt: Maus Monoclonal 52-PTP1C-SHP1 unconjugated
anti-Protein-tyrosine Phosphatase 1C (PTPN6) antibodyPTPN6 Reaktivität: Human, Maus, Ratte WB, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
- WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20 °C. Stable for 12 months from date of receipt.
- Haltbarkeit
- 12 months
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- Target
- SHP1 (PTPN6) (Protein-tyrosine Phosphatase 1C (PTPN6))
- Andere Bezeichnung
- PTPN6 (PTPN6 Produkte)
- Hintergrund
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Description: Modulates signaling by tyrosine phosphorylated cell surface receptors such as KIT and the EGF receptor/EGFR. The SH2 regions may interact with other cellular components to modulate its own phosphatase activity against interacting substrates. Together with MTUS1, induces UBE2V2 expression upon angiotensin II stimulation. Plays a key role in hematopoiesis.
Gene: PTPN6
- Molekulargewicht
- 67kDa
- Gen-ID
- 5777
- UniProt
- P29350
- Pathways
- JAK-STAT Signalweg, T-Zell Rezeptor Signalweg, TLR Signalweg, Nuclear Receptor Transcription Pathway, Positive Regulation of Peptide Hormone Secretion, Steroid Hormone Mediated Signaling Pathway, Response to Growth Hormone Stimulus, Regulation of Leukocyte Mediated Immunity, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, BCR Signaling
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