SIN3B Antikörper (Internal Region)

Produktnummer ABIN6265088

Produktdetails anti-SIN3B Antikörper

Target: SIN3B (SIN3 Transcription Regulator Homolog B (SIN3B))

Bindungsspezifität: Internal Region

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SIN3B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (IHC), Immunocytochemistry (ICC)

Spezifität: Sin3B Antibody detects endogenous levels of total Sin3B.

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human Sin3B, corresponding to a region within the internal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:1000, IHC 1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu SIN3B

Target: SIN3B (SIN3 Transcription Regulator Homolog B (SIN3B))

Andere Bezeichnung: SIN3B (SIN3B Produkte)

Synonyme: fj63d08 antikoerper, si:dkey-6n6.6 antikoerper, wu:fj63d08 antikoerper, 2810430C10Rik antikoerper, SIN3 transcription regulator family member B antikoerper, SIN3 transcription regulator family member B S homeolog antikoerper, transcriptional regulator, SIN3B (yeast) antikoerper, sin3b antikoerper, SIN3B antikoerper, sin3b.S antikoerper, Sin3b antikoerper

Hintergrund:

Description: Acts as a transcriptional repressor. Interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities. Interacts with MAD-MAX heterodimers by binding to MAD. The heterodimer then represses transcription by tethering SIN3B to DNA. Also forms a complex with FOXK1 which represses transcription. With FOXK1, regulates cell cycle progression probably by repressing cell cycle inhibitor genes expression.

Gene: SIN3B

Molekulargewicht: 130kDa

Gen-ID: 23309

UniProt: O75182