SPDYA Antikörper (Internal Region)

Produktnummer ABIN6265255

Produktdetails anti-SPDYA Antikörper

Target: SPDYA (Speedy Homolog A (SPDYA))

Bindungsspezifität: Internal Region

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SPDYA Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC)

Spezifität: SPDYA Antibody detects endogenous levels of total SPDYA.

Homologie: Pig,Bovine,Sheep,Rabbit,Dog

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human SPDYA, corresponding to a region within the internal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu SPDYA

Target: SPDYA (Speedy Homolog A (SPDYA))

Andere Bezeichnung: SPDYA (SPDYA Produkte)

Synonyme: zgc:101624 antikoerper, 4921517J08Rik antikoerper, 4930548B21Rik antikoerper, GS4 antikoerper, MLZ-465 antikoerper, Spdy1 antikoerper, RINGO antikoerper, SPDY1 antikoerper, RINGO3 antikoerper, RINGOA antikoerper, SPY1 antikoerper, Gs4 antikoerper, Lm23 antikoerper, Spy1 antikoerper, speedy homolog A (Xenopus laevis) antikoerper, speedy/RINGO cell cycle regulator family member A antikoerper, speedy/RINGO cell cycle regulator family, member A antikoerper, SPDYA antikoerper, spdya antikoerper, Spdya antikoerper

Hintergrund:

Description: Regulates the G1/S phase transition of the cell cycle by binding and activating CDK1 and CDK2 (PubMed:12972555). Contributes to CDK2 activation without promoting CDK2 phosphorylation, by inducing a conformation change of the CDK2 T-loop that obstructs the substrate-binding cleft prior to kinase activation (PubMed:28666995). Mediates cell survival during the DNA damage process through activation of CDK2 (PubMed:12839962).

Gene: SPDYA

Molekulargewicht: 36kDa

Gen-ID: 245711

UniProt: Q5MJ70