SREBF1 Antikörper
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- Target Alle SREBF1 Antikörper anzeigen
- SREBF1 (Sterol Regulatory Element Binding Transcription Factor 1 (SREBF1))
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Reaktivität
- Human, Ratte, Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser SREBF1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
- Spezifität
- SREBP-1 Antibody detects endogenous levels of total SREBP-1
- Kreuzreaktivität
- Human, Maus, Ratte (Rattus)
- Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human SREBP-1
- Isotyp
- IgG
- Top Product
- Discover our top product SREBF1 Primärantikörper
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- Applikationshinweise
- WB 1:500-1:2000 IHC 1:50-1:200, IF/ICC 1:100-1:500
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20 °C.Stable for 12 months from date of receipt
- Haltbarkeit
- 12 months
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Herbal SGR Formula Prevents Acute Ethanol-Induced Liver Steatosis via Inhibition of Lipogenesis and Enhancement Fatty Acid Oxidation in Mice." in: Evidence-based complementary and alternative medicine : eCAM, Vol. 2015, pp. 613584, (2015) (PubMed).
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Herbal SGR Formula Prevents Acute Ethanol-Induced Liver Steatosis via Inhibition of Lipogenesis and Enhancement Fatty Acid Oxidation in Mice." in: Evidence-based complementary and alternative medicine : eCAM, Vol. 2015, pp. 613584, (2015) (PubMed).
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- Target
- SREBF1 (Sterol Regulatory Element Binding Transcription Factor 1 (SREBF1))
- Andere Bezeichnung
- SREBP-1 (SREBF1 Produkte)
- Synonyme
- SREBP-1c antikoerper, SREBP1 antikoerper, bHLHd1 antikoerper, ADD-1 antikoerper, ADD1 antikoerper, D630008H06 antikoerper, SREBP-1 antikoerper, SREBP-1a antikoerper, SREBP1c antikoerper, Srebp1 antikoerper, SCREBP1 antikoerper, SREBP-1C antikoerper, SREBF1 antikoerper, srebp1 antikoerper, sterol regulatory element binding transcription factor 1 antikoerper, sterol regulatory element binding transcription factor 1 L homeolog antikoerper, sterol regulatory element binding protein-1 antikoerper, Sterol regulatory element Binding Protein antikoerper, SREBF1 antikoerper, Srebf1 antikoerper, srebf1.L antikoerper, SREBP-1 antikoerper, srebf1 antikoerper, sbp-1 antikoerper
- Hintergrund
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Description: Transcriptional activator required for lipid homeostasis. Regulates transcription of the LDL receptor gene as well as the fatty acid and to a lesser degree the cholesterol synthesis pathway (By similarity). Binds to the sterol regulatory element 1 (SRE-1) (5'-ATCACCCCAC-3'). Has dual sequence specificity binding to both an E-box motif (5'-ATCACGTGA-3') and to SRE-1 (5'-ATCACCCCAC-3').
Gene: SREBF1
- Molekulargewicht
- 122kDa
- Gen-ID
- 6720
- UniProt
- P36956
- Pathways
- AMPK Signaling, Caspase Kaskade in der Apoptose, Negative Regulation of Hormone Secretion, Regulation of Lipid Metabolism by PPARalpha
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