STAMBP Antikörper (C-Term)
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- Target Alle STAMBP Antikörper anzeigen
- STAMBP (STAM Binding Protein (STAMBP))
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Bindungsspezifität
- C-Term
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser STAMBP Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA
- Spezifität
- STAMBP Antibody detects endogenous levels of total STAMBP.
- Homologie
- Pig,Bovine,Horse,Sheep,Rabbit,Xenopus
- Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human STAMBP, corresponding to a region within C-terminal amino acids.
- Isotyp
- IgG
- Top Product
- Discover our top product STAMBP Primärantikörper
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- Applikationshinweise
- WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20 °C. Stable for 12 months from date of receipt.
- Haltbarkeit
- 12 months
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- Target
- STAMBP (STAM Binding Protein (STAMBP))
- Andere Bezeichnung
- STAMBP (STAMBP Produkte)
- Synonyme
- AMSH antikoerper, 5330424L14Rik antikoerper, 5730422L11Rik antikoerper, AW107289 antikoerper, Amsh antikoerper, mKIAA4198 antikoerper, stambp antikoerper, zgc:66147 antikoerper, STAM binding protein antikoerper, Stam binding protein antikoerper, STAM binding protein a antikoerper, STAMBP antikoerper, Stambp antikoerper, stambpa antikoerper
- Hintergrund
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Description: Zinc metalloprotease that specifically cleaves 'Lys-63'-linked polyubiquitin chains. Does not cleave 'Lys-48'-linked polyubiquitin chains (By similarity). Plays a role in signal transduction for cell growth and MYC induction mediated by IL-2 and GM-CSF. Potentiates BMP (bone morphogenetic protein) signaling by antagonizing the inhibitory action of SMAD6 and SMAD7. Has a key role in regulation of cell surface receptor-mediated endocytosis and ubiquitin-dependent sorting of receptors to lysosomes. Endosomal localization of STAMBP is required for efficient EGFR degradation but not for its internalization (By similarity). Involved in the negative regulation of PI3K-AKT-mTOR and RAS-MAP signaling pathways.
Gene: STAMBP
- Molekulargewicht
- 50 kDa
- Gen-ID
- 10617
- UniProt
- O95630
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