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STAMBP Antikörper (C-Term)

STAMBP Reaktivität: Human, Maus, Ratte WB, ELISA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6265307
  • Target Alle STAMBP Antikörper anzeigen
    STAMBP (STAM Binding Protein (STAMBP))
    Bindungsspezifität
    • 15
    • 10
    • 8
    • 8
    • 7
    • 3
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reaktivität
    • 44
    • 30
    • 19
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 56
    • 4
    Kaninchen
    Klonalität
    • 57
    • 3
    Polyklonal
    Konjugat
    • 24
    • 5
    • 5
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser STAMBP Antikörper ist unkonjugiert
    Applikation
    • 35
    • 22
    • 19
    • 13
    • 13
    • 7
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA
    Spezifität
    STAMBP Antibody detects endogenous levels of total STAMBP.
    Homologie
    Pig,Bovine,Horse,Sheep,Rabbit,Xenopus
    Aufreinigung
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human STAMBP, corresponding to a region within C-terminal amino acids.
    Isotyp
    IgG
    Top Product
    Discover our top product STAMBP Primärantikörper
  • Applikationshinweise
    WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20 °C. Stable for 12 months from date of receipt.
    Haltbarkeit
    12 months
  • Target
    STAMBP (STAM Binding Protein (STAMBP))
    Andere Bezeichnung
    STAMBP (STAMBP Produkte)
    Synonyme
    AMSH antikoerper, 5330424L14Rik antikoerper, 5730422L11Rik antikoerper, AW107289 antikoerper, Amsh antikoerper, mKIAA4198 antikoerper, stambp antikoerper, zgc:66147 antikoerper, STAM binding protein antikoerper, Stam binding protein antikoerper, STAM binding protein a antikoerper, STAMBP antikoerper, Stambp antikoerper, stambpa antikoerper
    Hintergrund

    Description: Zinc metalloprotease that specifically cleaves 'Lys-63'-linked polyubiquitin chains. Does not cleave 'Lys-48'-linked polyubiquitin chains (By similarity). Plays a role in signal transduction for cell growth and MYC induction mediated by IL-2 and GM-CSF. Potentiates BMP (bone morphogenetic protein) signaling by antagonizing the inhibitory action of SMAD6 and SMAD7. Has a key role in regulation of cell surface receptor-mediated endocytosis and ubiquitin-dependent sorting of receptors to lysosomes. Endosomal localization of STAMBP is required for efficient EGFR degradation but not for its internalization (By similarity). Involved in the negative regulation of PI3K-AKT-mTOR and RAS-MAP signaling pathways.

    Gene: STAMBP

    Molekulargewicht
    50 kDa
    Gen-ID
    10617
    UniProt
    O95630
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