TBC1D23 Antikörper (Internal Region)
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- Target Alle TBC1D23 Produkte
- TBC1D23 (TBC1 Domain Family, Member 23 (TBC1D23))
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Bindungsspezifität
- Internal Region
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser TBC1D23 Antikörper ist unkonjugiert
- Applikation
- Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)
- Spezifität
- TBC1D23 Antibody detects endogenous levels of total TBC1D23.
- Homologie
- Pig,Bovine,Horse,Sheep,Rabbit,Dog
- Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human TBC1D23, corresponding to a region within the internal amino acids.
- Isotyp
- IgG
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- Applikationshinweise
- WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20 °C. Stable for 12 months from date of receipt.
- Haltbarkeit
- 12 months
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- Target
- TBC1D23 (TBC1 Domain Family, Member 23 (TBC1D23))
- Andere Bezeichnung
- TBC1D23 (TBC1D23 Produkte)
- Synonyme
- RGD1307925 antikoerper, NS4ATP1 antikoerper, 4930451A13Rik antikoerper, AU015720 antikoerper, AU043671 antikoerper, AU043778 antikoerper, D030022P07Rik antikoerper, W51689 antikoerper, zgc:63756 antikoerper, TBC1 domain family, member 23 antikoerper, TBC1 domain family member 23 antikoerper, Tbc1d23 antikoerper, TBC1D23 antikoerper, tbc1d23 antikoerper
- Hintergrund
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Description: Putative Rab GTPase-activating protein which plays a role in vesicular trafficking (PubMed:28823707). Involved in endosome-to-Golgi trafficking. Acts as a bridging protein by binding simultaneously to golgins, including GOLGA1 and GOLGA4, located at the trans-Golgi, and to the WASH complex, located on endosome-derived vesicles (PubMed:29084197). Plays a role in brain development, including in cortical neuron positioning (By similarity). May also be important for neurite outgrowth, possibly through its involvement in membrane trafficking and cargo delivery, 2 processes that are essential for axonal and dendritic growth (By similarity). May act as a general inhibitor of innate immunity signaling, strongly inhibiting multiple TLR and dectin/CLEC7A-signaling pathways. Does not alter initial activation events, but instead affects maintenance of inflammatory gene expression several hours after bacterial lipopolysaccharide (LPS) challenge (By similarity).
Gene: TBC1D23
- Molekulargewicht
- 78 kDa
- Gen-ID
- 55773
- UniProt
- Q9NUY8
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