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TCTN1 Antikörper (N-Term)

TCTN1 Reaktivität: Ratte, Human, Maus WB, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6265507
  • Target Alle TCTN1 Antikörper anzeigen
    TCTN1 (Tectonic Family Member 1 (TCTN1))
    Bindungsspezifität
    • 15
    • 2
    • 1
    • 1
    N-Term
    Reaktivität
    Ratte, Human, Maus
    Wirt
    • 18
    Kaninchen
    Klonalität
    • 18
    Polyklonal
    Konjugat
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser TCTN1 Antikörper ist unkonjugiert
    Applikation
    • 18
    • 13
    • 13
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Spezifität
    TCTN1 Antibody detects endogenous levels of total TCTN1.
    Homologie
    Pig
    Aufreinigung
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human TCTN1, corresponding to a region within N-terminal amino acids.
    Isotyp
    IgG
  • Applikationshinweise
    WB 1:500-1:2000, IHC 1:50-1:200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20 °C. Stable for 12 months from date of receipt.
    Haltbarkeit
    12 months
  • Target
    TCTN1 (Tectonic Family Member 1 (TCTN1))
    Andere Bezeichnung
    TCTN1 (TCTN1 Produkte)
    Synonyme
    FLJ21127 antikoerper, JBTS13 antikoerper, TECT1 antikoerper, G730031O11Rik antikoerper, Tect1 antikoerper, RGD1566266 antikoerper, tectonic family member 1 antikoerper, tectonic family member 1 L homeolog antikoerper, TCTN1 antikoerper, tctn1.L antikoerper, tctn1 antikoerper, Tctn1 antikoerper
    Hintergrund

    Description: Component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes. Regulator of Hedgehog (Hh), required for both activation and inhibition of the Hh pathway in the patterning of the neural tube. During neural tube development, it is required for formation of the most ventral cell types and for full Hh pathway activation. Functions in Hh signal transduction to fully activate the pathway in the presence of high Hh levels and to repress the pathway in the absence of Hh signals. Modulates Hh signal transduction downstream of SMO and RAB23 (By similarity).

    Gene: TCTN1

    Molekulargewicht
    55-64kDa
    Gen-ID
    79600
    UniProt
    Q2MV58
    Pathways
    Tube Formation
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