TDGF1 Antikörper (Internal Region)

Produktnummer ABIN6265513

Produktdetails anti-TDGF1 Antikörper

Target: TDGF1 (Teratocarcinoma-Derived Growth Factor 1 (TDGF1))

Bindungsspezifität: Internal Region

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TDGF1 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Spezifität: TDGF1 Antibody detects endogenous levels of total TDGF1.

Homologie: Pig,Bovine,Sheep,Rabbit

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human TDGF1, corresponding to a region within the internal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu TDGF1

Target: TDGF1 (Teratocarcinoma-Derived Growth Factor 1 (TDGF1))

Andere Bezeichnung: TDGF1 (TDGF1 Produkte)

Synonyme: CR antikoerper, CRGF antikoerper, CRIPTO antikoerper, CR1 antikoerper, cripto antikoerper, cb85 antikoerper, tdgf1 antikoerper, wu:fe01d04 antikoerper, zgc:109829 antikoerper, Cripto-1 antikoerper, cr1 antikoerper, cr1a antikoerper, frl-1 antikoerper, frl1 antikoerper, xcr1 antikoerper, TDGF1 antikoerper, tdgf3 antikoerper, cripto-3 antikoerper, teratocarcinoma-derived growth factor 1 antikoerper, teratocarcinoma-derived growth factor 1, member 3 L homeolog antikoerper, teratocarcinoma-derived growth factor 1, member 1 antikoerper, TDGF1 antikoerper, Tdgf1 antikoerper, tdgf1 antikoerper, tdgf1.3.L antikoerper, tdgf1.1 antikoerper

Hintergrund:

Description: GPI-anchored cell membrane protein involved in Nodal signaling. Cell-associated TDGF1 acts as a Nodal coreceptor in cis. Shedding of TDGF1 by TMEM8A modulates Nodal signaling by allowing soluble TDGF1 to act as a Nodal coreceptor on other cells (PubMed:27881714). Could play a role in the determination of the epiblastic cells that subsequently give rise to the mesoderm (PubMed:11909953).

Gene: TDGF1

Molekulargewicht: 21kDa

Gen-ID: 6997

UniProt: P13385

Pathways: EGFR Signaling Pathway