THOC1 Antikörper (C-Term)
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- Target Alle THOC1 Antikörper anzeigen
- THOC1 (THO Complex 1 (THOC1))
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Bindungsspezifität
- C-Term
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Reaktivität
- Human, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser THOC1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
- Spezifität
- THOC1 Antibody detects endogenous levels of total THOC1.
- Homologie
- Pig,Bovine,Horse,Sheep,Rabbit,Dog,Xenopus
- Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human THOC1, corresponding to a region within C-terminal amino acids.
- Isotyp
- IgG
- Top Product
- Discover our top product THOC1 Primärantikörper
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anti-THO Complex 1 (THOC1) antibody
THOC1 Reaktivität: Human, Maus, Ratte WB, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-THO Complex 1 (THOC1) (C-Term) antibodyKO Validated THOC1 Reaktivität: Human WB, IF, IP, IHC (p), ICC, ChIP Wirt: Kaninchen Polyclonal unconjugated
anti-THO Complex 1 (THOC1) (AA 428-657) antibodyTHOC1 Reaktivität: Human WB, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-THO Complex 1 (THOC1) (C-Term) antibodyTHOC1 Reaktivität: Human, Maus, Ratte, Hund, Pferd, Kaninchen, Meerschweinchen, Rind (Kuh), Zebrafisch (Danio rerio), Saccharomyces cerevisiae WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-THO Complex 1 (THOC1) (AA 428-657) antibodyTHOC1 Reaktivität: Human WB, IHC, ELISA, ChIP Wirt: Kaninchen Polyclonal unconjugated
anti-THO Complex 1 (THOC1) (AA 511-560) antibodyTHOC1 Reaktivität: Human, Maus, Ratte, Hund, Pferd, Kaninchen, Meerschweinchen, Rind (Kuh), Affe, Huhn WB, IHC, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-THO Complex 1 (THOC1) (C-Term) antibodyTHOC1 Reaktivität: Human, Maus, Ratte WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-THO Complex 1 (THOC1) (AA 257-285), (N-Term) antibodyTHOC1 Reaktivität: Human WB Wirt: Maus Monoclonal 301CT40-5-1 unconjugated
anti-THO Complex 1 (THOC1) (AA 541-570), (C-Term) antibodyTHOC1 Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
anti-THO Complex 1 (THOC1) (AA 540-570), (C-Term) antibodyTHOC1 Reaktivität: Human WB, EIA Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
- WB 1:1000-3000, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20 °C. Stable for 12 months from date of receipt.
- Haltbarkeit
- 12 months
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- Target
- THOC1 (THO Complex 1 (THOC1))
- Andere Bezeichnung
- THOC1 (THOC1 Produkte)
- Hintergrund
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Description: Required for efficient export of polyadenylated RNA. Acts as component of the THO subcomplex of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and which specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export to the cytoplasm via the TAP/NFX1 pathway. The TREX complex is essential for the export of Kaposi's sarcoma-associated herpesvirus (KSHV) intronless mRNAs and infectious virus production. Regulates transcriptional elongation of a subset of genes. Involved in genome stability by preventing co-transcriptional R-loop formation.
Gene: THOC1
- Molekulargewicht
- 76 kDa
- Gen-ID
- 9984
- UniProt
- Q96FV9
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