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TICAM1 Antikörper (Internal Region)

TICAM1 Reaktivität: Human, Maus, Ratte WB, IHC, ELISA, ICC, IF Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6265566
  • Target Alle TICAM1 Antikörper anzeigen
    TICAM1 (Toll-Like Receptor Adaptor Molecule 1 (TICAM1))
    Bindungsspezifität
    • 5
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    Reaktivität
    • 25
    • 9
    • 2
    • 2
    Human, Maus, Ratte
    Wirt
    • 22
    • 4
    • 3
    Kaninchen
    Klonalität
    • 25
    • 4
    Polyklonal
    Konjugat
    • 22
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser TICAM1 Antikörper ist unkonjugiert
    Applikation
    • 20
    • 6
    • 6
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)
    Spezifität
    TICAM1 Antibody detects endogenous levels of total TICAM1.
    Homologie
    Pig,Zebrafish,Bovine,Horse,Sheep,Dog,Chicken
    Aufreinigung
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human TICAM1, corresponding to a region within the internal amino acids.
    Isotyp
    IgG
    Top Product
    Discover our top product TICAM1 Primärantikörper
  • Applikationshinweise
    WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20 °C. Stable for 12 months from date of receipt.
    Haltbarkeit
    12 months
  • Target
    TICAM1 (Toll-Like Receptor Adaptor Molecule 1 (TICAM1))
    Andere Bezeichnung
    TICAM1 (TICAM1 Produkte)
    Synonyme
    IIAE6 antikoerper, MyD88-3 antikoerper, PRVTIRB antikoerper, TICAM-1 antikoerper, TRIF antikoerper, AW046014 antikoerper, AW547018 antikoerper, trif antikoerper, toll like receptor adaptor molecule 1 antikoerper, toll-like receptor adaptor molecule 1 antikoerper, TICAM1 antikoerper, Ticam1 antikoerper, ticam1 antikoerper
    Hintergrund

    Description: Involved in innate immunity against invading pathogens. Adapter used by TLR3 and TLR4 (through TICAM2) to mediate NF-kappa-B and interferon-regulatory factor (IRF) activation, and to induce apoptosis. Ligand binding to these receptors results in TRIF recruitment through its TIR domain. Distinct protein-interaction motifs allow recruitment of the effector proteins TBK1, TRAF6 and RIPK1, which in turn, lead to the activation of transcription factors IRF3 and IRF7, NF-kappa-B and FADD respectively.

    Gene: TICAM1

    Molekulargewicht
    76kDa
    Gen-ID
    148022
    UniProt
    Q8IUC6
    Pathways
    TLR Signalweg, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Hepatitis C, Toll-Like Receptors Cascades
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