TPMT Antikörper (N-Term)
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- Target Alle TPMT Antikörper anzeigen
- TPMT (Thiopurine S-Methyltransferase (TPMT))
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Bindungsspezifität
- N-Term
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser TPMT Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- Spezifität
- TPMT Antibody detects endogenous levels of total TPMT.
- Homologie
- Bovine,Horse,Rabbit
- Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human TPMT, corresponding to a region within N-terminal amino acids.
- Isotyp
- IgG
- Top Product
- Discover our top product TPMT Primärantikörper
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- Applikationshinweise
- WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20 °C. Stable for 12 months from date of receipt.
- Haltbarkeit
- 12 months
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- Target
- TPMT (Thiopurine S-Methyltransferase (TPMT))
- Andere Bezeichnung
- TPMT (TPMT Produkte)
- Synonyme
- MGC84277 antikoerper, AW106912 antikoerper, NHLRC1 antikoerper, thiopurine S-methyltransferase L homeolog antikoerper, thiopurine S-methyltransferase, tandem duplicate 2 antikoerper, thiopurine S-methyltransferase TpmT antikoerper, thiopurine S-methyltransferase antikoerper, Thiopurine S-methyltransferase antikoerper, thiopurine methyltransferase antikoerper, tpmt.L antikoerper, tpmt.2 antikoerper, tpmT antikoerper, MCA0794 antikoerper, Pnap_4948 antikoerper, Hhal_1383 antikoerper, TK90_1044 antikoerper, Slit_1144 antikoerper, Tint_0842 antikoerper, Fbal_3334 antikoerper, Celly_3188 antikoerper, Weevi_1737 antikoerper, Psefu_2696 antikoerper, Metme_3860 antikoerper, Tpmt antikoerper, TPMT antikoerper
- Hintergrund
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Description: Catalyzes the S-methylation of thiopurine drugs such as 6-mercaptopurine (also called mercaptopurine, 6-MP or its brand name Purinethol) and 6-thioguanine (also called tioguanine or 6-TG) using S-adenosyl-L-methionine as the methyl donor (PubMed:657528, PubMed:18484748). TPMT activity modulates the cytotoxic effects of thiopurine prodrugs. A natural substrate for this enzyme has yet to be identified.
Gene: TPMT
- Molekulargewicht
- 28kDa
- Gen-ID
- 7172
- UniProt
- P51580
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