TRADD Antikörper (N-Term)
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- Target Alle TRADD Antikörper anzeigen
- TRADD (TNFRSF1A-Associated Via Death Domain (TRADD))
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Bindungsspezifität
- N-Term
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser TRADD Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
- Spezifität
- TRADD Antibody detects endogenous levels of total TRADD.
- Homologie
- Pig,Bovine,Sheep
- Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human TRADD, corresponding to a region within N-terminal amino acids.
- Isotyp
- IgG
- Top Product
- Discover our top product TRADD Primärantikörper
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- Applikationshinweise
- WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20 °C. Stable for 12 months from date of receipt.
- Haltbarkeit
- 12 months
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- Target
- TRADD (TNFRSF1A-Associated Via Death Domain (TRADD))
- Andere Bezeichnung
- TRADD (TRADD Produkte)
- Synonyme
- TRADD antikoerper, Hs.89862 antikoerper, 9130005N23Rik antikoerper, AA930854 antikoerper, wu:fc59e02 antikoerper, zgc:103556 antikoerper, tradd antikoerper, TNFRSF1A associated via death domain antikoerper, conjugal transfer protein D antikoerper, TNFRSF1A-associated via death domain antikoerper, TNFRSF1A-associated via death domain L homeolog antikoerper, tnfrsf1a-associated via death domain antikoerper, TRADD antikoerper, traDd antikoerper, Tradd antikoerper, tradd.L antikoerper, tradd antikoerper
- Hintergrund
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Description: The nuclear form acts as a tumor suppressor by preventing ubiquitination and degradation of isoform p19ARF/ARF of CDKN2A by TRIP12: acts by interacting with TRIP12, leading to disrupt interaction between TRIP12 and isoform p19ARF/ARF of CDKN2A (By similarity). Adapter molecule for TNFRSF1A/TNFR1 that specifically associates with the cytoplasmic domain of activated TNFRSF1A/TNFR1 mediating its interaction with FADD. Overexpression of TRADD leads to two major TNF-induced responses, apoptosis and activation of NF-kappa-B.
Gene: TRADD
- Molekulargewicht
- 34kDa
- Gen-ID
- 8717
- UniProt
- Q15628
- Pathways
- NF-kappaB Signalweg, Apoptose, Caspase Kaskade in der Apoptose, Positive Regulation of Endopeptidase Activity, Hepatitis C
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