TRAF1 Antikörper (C-Term)
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- Target Alle TRAF1 Antikörper anzeigen
- TRAF1 (TNF Receptor-Associated Factor 1 (TRAF1))
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Bindungsspezifität
- C-Term
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser TRAF1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- Spezifität
- TRAF1 Antibody detects endogenous levels of total TRAF1.
- Homologie
- Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken
- Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human TRAF1, corresponding to a region within C-terminal amino acids.
- Isotyp
- IgG
- Top Product
- Discover our top product TRAF1 Primärantikörper
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- Applikationshinweise
- WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20 °C. Stable for 12 months from date of receipt.
- Haltbarkeit
- 12 months
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- Target
- TRAF1 (TNF Receptor-Associated Factor 1 (TRAF1))
- Andere Bezeichnung
- TRAF1 (TRAF1 Produkte)
- Synonyme
- CG3048 antikoerper, DTRAF antikoerper, DTRAF1 antikoerper, Dmel\\CG3048 antikoerper, TRAF antikoerper, TRAF1 antikoerper, Traf1 antikoerper, dTRAF antikoerper, dTRAF1 antikoerper, dTraf1 antikoerper, dtraf1 antikoerper, traf1 antikoerper, traf4 antikoerper, DKFZp469G032 antikoerper, EBI6 antikoerper, MGC:10353 antikoerper, 4732496E14Rik antikoerper, TNF receptor associated factor 1 antikoerper, TNF-receptor-associated factor 4 antikoerper, TNF receptor-associated factor 1 antikoerper, TRAF1 antikoerper, Traf4 antikoerper, Traf1 antikoerper, traf1 antikoerper
- Hintergrund
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Description: Adapter molecule that regulates the activation of NF-kappa-B and JNK. Plays a role in the regulation of cell survival and apoptosis. The heterotrimer formed by TRAF1 and TRAF2 is part of a E3 ubiquitin-protein ligase complex that promotes ubiquitination of target proteins, such as MAP3K14. The TRAF1/TRAF2 complex recruits the antiapoptotic E3 protein-ubiquitin ligases BIRC2 and BIRC3 to TNFRSF1B/TNFR2.
Gene: TRAF1
- Molekulargewicht
- 46 kDa
- Gen-ID
- 7185
- UniProt
- Q13077
- Pathways
- NF-kappaB Signalweg, Apoptose, Cell-Cell Junction Organization, Asymmetric Protein Localization
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